Now showing items 1-2 of 2

    • Synaptic Wnt/GSK3β Signaling Hub in Autism 

      Caracci, M.O.; Avila, M.E.; De Ferrari, G.V. (HINDAWI PUBLISHING CORP, 2016)
      Hundreds of genes have been associated with autism spectrum disorders (ASDs) and the interaction of weak and de novo variants derive from distinct autistic phenotypes thus making up the "spectrum." The convergence of these ...
    • Wnt/β-catenin signaling stimulates the expression and synaptic clustering of the autism-associated Neuroligin 3 gene 

      Medina, M.A.; Andrade, V.M.; Caracci, M.O.; Avila, M.E.; Verdugo, D.A.; Vargas, M.F.; Ugarte, G.D.; Reyes, A.E.; Opazo, C.; De Ferrari, G.V. (Nature Publishing Group, 2018-12)
      Synaptic abnormalities have been described in individuals with autism spectrum disorders (ASD). The cell-adhesion molecule Neuroligin-3 (Nlgn3) has an essential role in the function and maturation of synapses and NLGN3 ...