Environmental reprogramming of the expression of protein kinase CK2β subunit in fish
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Fecha
2001
Autores
Profesor/a Guía
Facultad/escuela
Idioma
en
Título de la revista
ISSN de la revista
Título del volumen
Editor
Springer
Nombre de Curso
Licencia CC
Licencia CC
Resumen
The dramatic segregation of the nucleolar components in winter-acclimatized carp is the most striking cellular-phenotypical feature observed during the seasonal adaptation of this fish toward the circannual changes in its habitat. Our studies also show that the carp habitat temperature and photoperiod winter conditions provoke a remarkable reduction of both rRNA transcription and the processing of their precursors. To gain knowledge on the mechanisms involved in the regulation of nucleolar activity during the seasonal adaptation process, we studied the behavior of some genes, specifically snoRNA U3 and protein kinase CK2. Consistent with the reduction in the synthesis and processing of pre-rRNA observed during the cold season, the level of CK2β expression decreases in winter when compared to that attained in summer. Similarly, in winter, liver and kidney cells contain lower levels of CK2β subunit protein compared to summer. CK2 is associated with or modifies different factors and enzymes involved in the nucleolar activity; therefore, its higher or lower content could be part of the molecular mechanisms underlying the nucleolar seasonal changes that occur during the compensatory acclimatization process.
Notas
Indexación: Scopus.
Palabras clave
Carp, Fish acclimatization, Nucleolus, Protein kinase CK2β subunit, animal cell, animal tissue, beta chain, cell activity, controlled study, enzyme modification, enzyme subunit, gene activity, kidney cell, liver cell, temperature acclimatization, RNA processing, RNA synthesis
Citación
Molecular and Cellular Biochemistry Volume 227, Issue 1-2, 2001, Pages 107-112
DOI
DOI: 10.1023/A:1013137612369