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dc.contributor.authorSandoval, Catalina
dc.contributor.authorArriagada, Franco S.
dc.contributor.authorDe la Fuente, Julio R.
dc.contributor.authorSanchez, Susana A.
dc.contributor.authorMorales, Javier
dc.contributor.authorPizarro, Nancy
dc.contributor.authorNonelle, Santi
dc.contributor.authorGunther, German
dc.date.accessioned2016-06-28T02:13:40Z
dc.date.available2016-06-28T02:13:40Z
dc.date.issued2016
dc.identifier.citationJ. Braz. Chem. Soc. vol.27 no.2 São Paulo Feb. 2016es
dc.identifier.issn1678-4790
dc.identifier.otherhttp://dx.doi.org/10.5935/0103-5053.20150306
dc.identifier.urihttp://repositorio.unab.cl/xmlui/handle/ria/847
dc.descriptionIndexación: Web of Science; Scielo.es
dc.description.abstractGlycolipids are biomolecules composed of a lipid chain (lipophilic) and a monosaccharide or oligosaccharide as hydrophilic group. Their chemical structure and biological role make them undoubtedly good candidates for a large and continuously growing number of biotechnological applications. Mannose is a carbohydrate present on membrane glycolipids of a wide number of pathogenic microorganisms (bacteria, fungi, protozoa, and viruses) and specifically recognized by several lectins. We synthesized a mannose derivative linked through a short methylene chain to a pyrene moiety which behaves as a surfactant, able to aggregate, and retains the photophysical properties of pyrene: showing comparable absorption and emission spectra, having lower fluorescence quantum yield and the ability to form excimer, and finally the ability to produce O2(1Δg) with high quantum yields. Thus, this novel molecule would open future applications for detection (fluorescence) or inactivation (singlet oxygen) of bacterial pathogens, viruses, tumor cells, or particular cells.es
dc.description.urihttp://ref.scielo.org/ym8zyp
dc.language.isoenes
dc.publisherSociedade Brasileira de Químicaes
dc.subjectPyrenees
dc.subjectMannosees
dc.subjectExcimeres
dc.subjectSinglet oxygenes
dc.subjectMicelleses
dc.titleSynthesis, Physicochemical and Photophysical Characterization of 4-(1-Pyrenyl)-butyl-α-D-mannopyranosidees
dc.typeArticlees


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