Examinando por Autor "Neumann B., Megan"
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Ítem Fortuna and Serendipity: history of some drugs used in Pediatric Intensive Care(Sociedad Chilena de Pediatria, 2022-07) Donoso F., Alejandro; Neumann B., Megan; Arriagada S., DanielaSerendipity has played a crucial role in the history of many different areas of science, including modern medicine. This corresponds to the ability to make a discovery, which occurs accidentally or by chance, in combination with the sagacity of the observer. Many of the most important and revolutionary findings in medical science, specifically pharmacology, involved serendipitous events of a nature. Some examples related to drug discovery and pharmacological research are briefly reviewed, such as the history of benzodiazepines, chloral hydrate, clonidine, warfarin, Ringer’s solution, valproic acid, barbiturates, penicillin and insulin, in which there were events related to serendipity. All these drugs or their derivatives are currently in frequent use in Intensive Care Units. © 2022, Sociedad Chilena de Pediatria. All rights reserved.Ítem Penetrating trauma of vertebral artery. From damage control to endovascular(Sociedad de Cirujanos de Chile, 2022) Ramos P., Juan P.; Neumann B., Megan; Zinco A., Analía; Ottolino L., Pablo R.Introduction: Traumatic involvement of the vertebral artery is extremely rare and difficult to diagnose. Objective: To provide clinical evidence by reviewing a case series. Materials and Method: We analyze four cases of penetrating trauma with involvement of the vertebral artery between 2020 and 2021, managed in the trauma and emergency unit of the Dr. Sótero del Río Care Complex. Results: Four clinical cases are presented describing diagnosis and management process. Discussion: There is little evidence of traumatic involvement of the vertebral artery. Recognizing its complex anatomy and varied clinic are transcendental for its proper management. When this type of lesion is suspected, computed tomography angiography is the choice study when hemodynamically stable. The range of therapeutic options include observation, antithrombotic or antiplatelet therapy, endovascular therapy or open surgery. Conclusion: Penetrating trauma of the vertebral artery is an uncommon condition, however, its diagnosis and management should be known to the surgeon. © 2022, Sociedad de Cirujanos de Chile. All rights reserved.