Zebrafish as animal model for aquaculture nutrition research
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Fecha
2014
Profesor/a Guía
Facultad/escuela
Idioma
en
Título de la revista
ISSN de la revista
Título del volumen
Editor
Frontiers Media S.A.
Nombre de Curso
Licencia CC
Atribution 4.0 International (CC BY 4.0)
Licencia CC
https://creativecommons.org/licenses/by/4.0/deed.es
Resumen
The aquaculture industry continues to promote the diversification of ingredients used
in aquafeed in order to achieve a more sustainable aquaculture production system. The
evaluation of large numbers of diets in aquaculture species is costly and requires time consuming trials in some species. In contrast, zebrafish (Danio rerio) can solve these
drawbacks as an experimental model, and represents an ideal organism to carry out
preliminary evaluation of diets. In addition, zebrafish has a sequenced genome allowing
the efficient utilization of new technologies, such as RNA-sequencing and genotyping
platforms to study the molecular mechanisms that underlie the organism’s response
to nutrients. Also, biotechnological tools like transgenic lines with fluorescently labeled
neutrophils that allow the evaluation of the immune response in vivo, are readily available in
this species. Thus, zebrafish provides an attractive platform for testing many ingredients to
select those with the highest potential of success in aquaculture. In this perspective article
aspects related to diet evaluation in which zebrafish can make important contributions to
nutritional genomics and nutritional immunity are discussed.
Notas
Indexación: Scopus.
Palabras clave
Zebrafish, Aquaculture Nutrition, Diet Evaluation, Nutritional Genomics, Nutritional Immunity
Citación
Frontiers in Genetics. Volume 5, Issue SEP. 2014. Article number 313
DOI
10.3389/fgene.2014.00313