Fortuna and Serendipity: history of some drugs used in Pediatric Intensive Care
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Archivos
Fecha
2022-07
Profesor/a Guía
Facultad/escuela
Idioma
es
Título de la revista
ISSN de la revista
Título del volumen
Editor
Sociedad Chilena de Pediatria
Nombre de Curso
Licencia CC
CC BY 4.0 DEED
Attribution 4.0 International
Licencia CC
https://creativecommons.org/licenses/by/4.0/
Resumen
Serendipity has played a crucial role in the history of many different areas of science, including modern medicine. This corresponds to the ability to make a discovery, which occurs accidentally or by chance, in combination with the sagacity of the observer. Many of the most important and revolutionary findings in medical science, specifically pharmacology, involved serendipitous events of a nature. Some examples related to drug discovery and pharmacological research are briefly reviewed, such as the history of benzodiazepines, chloral hydrate, clonidine, warfarin, Ringer’s solution, valproic acid, barbiturates, penicillin and insulin, in which there were events related to serendipity. All these drugs or their derivatives are currently in frequent use in Intensive Care Units. © 2022, Sociedad Chilena de Pediatria. All rights reserved.
Notas
Indexación: Scopus.
Palabras clave
Barbituric, Benzodiazepines, Medicine History, Penicillin, Ringer´s Solution, Serendipity
Citación
Andes Pediatrica, Volume 93, Issue 4, Pages 591 - 598, July-August 2022
DOI
10.32641/andespediatr.v93i4.4424