Eficacia analgésica de ketoprofeno + paracetamol y meloxicam + paracetamol de uso pre y postoperatorio en cirugía de desinclusión de terceros molares inferiores que requieran osteotomía
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Fecha
2015
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es
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Universidad Andrés Bello (Chile)
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Licencia CC
Licencia CC
Resumen
Objetivo: En el presente estudio se evaluó y comparó la efectividad de los analgésicos meloxicam 15mg y ketoprofeno 200mg en combinación con paracetamol 1gr, de uso preoperatorio en pacientes que fueron sometidos a desinclusión de terceros molares inferiores, con el fin de establecer el mejor tratamiento para la reducción del dolor postoperatorio. Materiales y métodos: Se evaluó la percepción dolorosa de 41 pacientes sometidos a cirugía, a través de la escala visual análoga (EVA), en las horas 0, 2, 5, y 8 para comprobar el efecto analgésico preventivo los fármacos, y en las horas 24 y 48 para comprobar el mejor tratamiento postoperatorio mediato entre ambos fármacos. Adicionalmente se evalúo la relación entre el tiempo de duración de la cirugía y la percepción dolorosa postoperatoria de los pacientes, y el efecto analgésico de ambos fármacos en cada género por separado. Resultados: Ambos fármacos no mostraron diferencias significativas a las horas estudiadas (P>0,05) cuando se compararon entre ellos. No existió correlación entre ketoprofeno (r=0,0092) y meloxicam (r=0,184) con el tiempo de duración intraoperatorio. Cuando se estudió a los pacientes por género, se encontraron diferencias significativas a las 48 horas, siendo más efectivo el meloxicam (P<0,05) que el ketoprofeno en mujeres, y más efectivo el ketoprofeno (P<0,005) que el meloxicam en hombres. Conclusiones: Como analgesia preventiva en este estudio, la utilización de ketoprofeno o meloxicam no pudo ser demostrada, sin embargo se recomienda el uso de ambos esquemas farmacológicos como tratamiento mediato para la disminución del dolor postoperatorio en cirugía de desinclusión de terceros molares mandibulares.
Objective: This study evaluated and compared the effectiveness of meloxicam and ketoprofen analgesics in combination with paracetamol preoperative use in patients who underwent third molars surgery in order to establish the best treatment for the reduction of postoperative pain. Materials and method: Pain perception of 41 patients undergoing surgery was evaluated through visual analogue scale (VAS) at times 0, 2, 5, and 8 to test the effect preemptive analgesic drugs, and 24 and 48 hours to verify the better postoperative treatment mediate between the two drugs. Additionally the relationship between the duration of surgery and postoperative pain perception of patients and the analgesic effect of both drugs was compared in each genre. Results: Both drugs showed no significant differences at times studied (P > 0.05) when compared with each other. There was no correlation between ketoprofen (r = 0.0092) and meloxicam (r = 0.184) with intraoperative time duration. When the patients were studied by gender, significant differences were found at 48 hours, meloxicam was found to be more effective in women than ketoprofen ( P < 0.05), and ketoprofen was more effective in men than meloxicam ( P < 0.05). Conclusions: As a preventive analgesia in this study, the use of meloxicam or ketoprofen could not be tested, however the use of both pharmacological treatments is recommended for decreasing postoperative pain in third molar surgery.
Objective: This study evaluated and compared the effectiveness of meloxicam and ketoprofen analgesics in combination with paracetamol preoperative use in patients who underwent third molars surgery in order to establish the best treatment for the reduction of postoperative pain. Materials and method: Pain perception of 41 patients undergoing surgery was evaluated through visual analogue scale (VAS) at times 0, 2, 5, and 8 to test the effect preemptive analgesic drugs, and 24 and 48 hours to verify the better postoperative treatment mediate between the two drugs. Additionally the relationship between the duration of surgery and postoperative pain perception of patients and the analgesic effect of both drugs was compared in each genre. Results: Both drugs showed no significant differences at times studied (P > 0.05) when compared with each other. There was no correlation between ketoprofen (r = 0.0092) and meloxicam (r = 0.184) with intraoperative time duration. When the patients were studied by gender, significant differences were found at 48 hours, meloxicam was found to be more effective in women than ketoprofen ( P < 0.05), and ketoprofen was more effective in men than meloxicam ( P < 0.05). Conclusions: As a preventive analgesia in this study, the use of meloxicam or ketoprofen could not be tested, however the use of both pharmacological treatments is recommended for decreasing postoperative pain in third molar surgery.
Notas
Tesis (Cirujano Dentista)
Palabras clave
Analgesia preventiva, Dolor postoperatorio, Analgésicos antiinflamatorios no esteroidales, Cirugía de terceros molares