Meso and racemic 1,1-bis (benzylsulfinyl)-2-ethylbutane. A b-disulfoxide pro-ligand with steric restrictions
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Archivos
Fecha
2016
Autores
Profesor/a Guía
Facultad/escuela
Idioma
en
Título de la revista
ISSN de la revista
Título del volumen
Editor
Sociedad Chilena de Quimica
Nombre de Curso
Licencia CC
Licencia CC
Resumen
Coordination chemistry of disulfoxides is of interest in inorganic chemistry given the well-known metal coordination through oxygen or sulfur atoms.1
Ethylene and propylene bridged disulfoxide pro-ligands, coordinate to metals, forming coordinated and chelated complexes, demonstrating its flexibility in the
formation of such complexes.2 Some of these compounds have demonstrated interesting properties in medicinal chemistry3
and asymmetric catalysis4
and their
synthesis is of importance for bioorganic studies. The presence of two stereogenic centers allows the existence of the meso and racemic forms in disulfoxides.
Previous studies on b-disulfoxides5
in our laboratories have led to the synthesis and spectroscopic study (1
H-NMR, FT-IR) of both diastereomeric forms. In this
work we report the synthesis and structural analysis of meso-(2)- and racemic-(3)-1,1-bis(benzylsulfinyl)-2-ethylbutane (Scheme1), with high steric requirement
around both sulfinyl groups when a branched aliphatic carbon chain is introduced in the a-carbon. An increase in selectivity for small radius metal ions was
achieved by compression of the pro-ligand coordination radius. These kind of compounds have not been previously studied
Notas
Indexación: Scopus.
Palabras clave
Inorganic Chemistry, Benzylsulfinyl, Bridged Dsulfoxide Pro-ligands
Citación
Journal of the Chilean Chemical Society. Volume 61, Issue 4, Pages 3157 - 3159. 2016
DOI
10.4067/s0717-97072016000400001