Transfer of T6SSSPI-19from Salmonella Gallinarum to Salmonella Typhimurium Lacking T6SSSPI-6Complements its Colonization Defect in Mice
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Archivos
Fecha
2023-06
Profesor/a Guía
Facultad/escuela
Idioma
en
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Editor
Sciendo
Nombre de Curso
Licencia CC
CC BY-NC-ND 4.0 Attribution-NonCommercial-NoDerivatives 4.0 International Deed
Licencia CC
https://creativecommons.org/licenses/by-nc-nd/4.0/
Resumen
Salmonella genus harbors five Type VI Secretion System (T6SS) gene clusters. The T6SS encoded in SPI-6 (T6SSSPI-6) contributes to Salmonella Typhimurium colonization of chickens and mice, while the T6SS encoded in SPI-19 (T6SSSPI-19) of Salmonella Gallinarum contributes to chicken colonization. Interestingly, the T6SSSPI-19 of Salmonella Gallinarum complemented the defect in chicken colonization of a Salmonella Typhimurium strain that lacks the T6SSSPI-6, suggesting that both T6SSs are interchangeable. Here we show that the transfer of Salmonella Gallinarum T6SSSPI-19 complemented the defect in mice colonization of a Salmonella Typhimurium ΔT6SSSPI-6 strain, indicating that both T6SSs are functionally redundant during host colonization. © 2023 David Pezoa et al., published by Sciendo.
Notas
Indexación: Scopus
Palabras clave
Colonization, Mice, Salmonella Typhimurium, SPI-19, T6SS
Citación
Polish Journal of Microbiology. Volume 72, Issue 2, Pages 215 - 219. June 2023
DOI
10.33073/pjm-2023-017