Catalán, L.E.Marín, K.C.Altamirano H.C.Fritis, M.C.Chamy M.C.2021-06-222021-06-222007-12MoleculesOpen AccessVolume 12, Issue 12, Pages 2605 - 2620December 20071420-3049http://repositorio.unab.cl/xmlui/handle/ria/19148Indexación: Scopus.A route for the degradation of the side chain of ent-labdane derivatives has been devised, giving the useful synthon 2β,12-dihydroxy-13,14,15,16,17- pentanor-ent-labdane-8-one (8). The use of this compound in the preparation of terpenylquinone derivatives shall be reported elsewhere. In addition we have synthesized the compound 2β,12-diacetoxy-8β,17-epoxy-13,14,15,16- tetranor-ent-labdane (10), which upon catalytic epoxide ring opening in alkaline or acid media gave rise in all cases to the formation of tricyclic compounds. © 2007 by MDPI.enEnt-labdanesSelective degradationsUnsaturated side chainArtículo10.3390/12122605