Olivares M., SebastiánCampaña V., GonzaloReadi V., AlejandroRodríguez G., Marcelo2024-11-132024-11-132022Revista de Cirugia, Volume 74, Issue 2, Pages 157 - 164, 20222452-4557https://repositorio.unab.cl/handle/ria/61931Indexación: Scopus.Aim: To evaluate postoperative complications and clinical evolution in patients undergoing colectomies and anastomosis with two preoperative strategies, mechanical bowel preparation alone (MBP) and mechanical bowel preparation with oral antibiotics (MBP+OA). Materials and Method: Retrospective study, with defined inclusion and exclusion criteria. Variables studied: preoperative demographic characteris-tics, surgical intervention, anastomotic location, anastomotic leakage (AL), surgical site infection (SSI), postoperative intestinal transit, Clostridium difficile (CD) infection and hospital stay. Statistical analysis, bivariate and multivariate models were performed. Results: 216 patients studied, 149 were MBP group and 67 MBP+OA group. The group MBP had higher rates of AL (7.38% vs. 0%, p = 0.011). For left-sided colectomies, AL rate in both groups had a higher difference in the middle rectum, with no cases in the MBP+OA group (0% vs. 50%, p = 0.019). For right colectomies, the AL rates were similar in both groups. SSI was higher in MBP group (4.7% vs. 0%, p = 0.037). The bowel transit recovery was faster for MBP+OA group, determining less hospital stay (3.98 days vs. 6.39 days, p = 0.001). The group MBP+OA had a higher rate of CD colitis, 4.48% (p = 0.008). Discussion and Conclusion: These results suggest that preoperative oral antibiotic with mechanical bowel preparation could help to prevent anastomotic leaks in left-sided colectomies, also avoid surgical site infection, favoring the recovery of postoperative bowel transit, reducing hospital stay. The association to CD should be examined in larger studies. © 2022, Sociedad de Cirujanos de Chile. All rights reserved.esAnastomotic leakBowel preparationColorectal surgeryOral antibioticsEstudio comparativo en pacientes sometidos a cirugía colorrectal con preparación mecánica exclusiva y preparación mecánica con antibióticos oralesComplications and postoperative clinical evolution in patients undergoing colorectal surgery with mechanical preparation alone and mechanical preparation with oral antibioticsArtículoAttribution 4.0 International CC BY 4.0 Deed10.35687/s2452-454920220021331