Bahamondes B., CarlosGodoy O., Jorge2013-12-192016-05-312013-12-192016-05-312007Revista médica de Chile, Vol. 135, N° 3, pp. 370-374, 2007.0034-9887http://repositorio.unab.cl/xmlui/handle/ria/2271Indexación: ScieloGingival enlargement can be an adverse effect of ciclosporine A and nifedipine use. It has a high relapse rate if the drugs are not discontinued. There is a genetic predisposition to the development of this condition and dental biofilm can also play a role. We report a 64 years old male who received a renal allograft and was treated with cyclosporine and nifedipine. He required six surgical interventions for generalized gingival enlargement. After the sixth relapse, the patient was subjected to a periodontal treatment to eliminate the dental biofilm, which decreased the rate of recurrence of gingival enlargement.esBiofilmCyclosporineGingival hyperplasiaHiperplasia gingivalCiclosporinaArtículo