Donoso F., AlejandroNeumann B., MeganArriagada S., Daniela2023-11-102023-11-102022-07Andes Pediatrica, Volume 93, Issue 4, Pages 591 - 598, July-August 20222452-6053https://repositorio.unab.cl/xmlui/handle/ria/53914Indexación: Scopus.Serendipity has played a crucial role in the history of many different areas of science, including modern medicine. This corresponds to the ability to make a discovery, which occurs accidentally or by chance, in combination with the sagacity of the observer. Many of the most important and revolutionary findings in medical science, specifically pharmacology, involved serendipitous events of a nature. Some examples related to drug discovery and pharmacological research are briefly reviewed, such as the history of benzodiazepines, chloral hydrate, clonidine, warfarin, Ringer’s solution, valproic acid, barbiturates, penicillin and insulin, in which there were events related to serendipity. All these drugs or their derivatives are currently in frequent use in Intensive Care Units. © 2022, Sociedad Chilena de Pediatria. All rights reserved.esBarbituricBenzodiazepinesMedicine HistoryPenicillinRinger´s SolutionSerendipityArtículoCC BY 4.0 DEED Attribution 4.0 International10.32641/andespediatr.v93i4.4424