Sandoval, C.Arriagada, F.S.De La Fuente, J.R.Sanchez, S.A.Morales, J.Pizarro, N.Nonell, S.Gunther, G.2017-08-182017-08-182016-02J. Braz. Chem. Soc. vol.27 no.2 São Paulo Feb. 20160103-5053http://dx.doi.org/10.5935/0103-5053.20150306http://repositorio.unab.cl/xmlui/handle/ria/3977Indexación: Web of Science; Scopus; Scielo.Glycolipids are biomolecules composed of a lipid chain (lipophilic) and a monosaccharide or oligosaccharide as hydrophilic group. Their chemical structure and biological role make them undoubtedly good candidates for a large and continuously growing number of biotechnological applications. Mannose is a carbohydrate present on membrane glycolipids of a wide number of pathogenic microorganisms (bacteria, fungi, protozoa, and viruses) and specifically recognized by several lectins. We synthesized a mannose derivative linked through a short methylene chain to a pyrene moiety which behaves as a surfactant, able to aggregate, and retains the photophysical properties of pyrene: showing comparable absorption and emission spectra, having lower fluorescence quantum yield and the ability to form excimer, and finally the ability to produce O-2((1)Delta(g)) with high quantum yields. Thus, this novel molecule would open future applications for detection (fluorescence) or inactivation (singlet oxygen) of bacterial pathogens, viruses, tumor cells, or particular cells.enPyreneMannoseExcimerSinglet oxygenMicellesArtículo