Hidalgo, María E.De la Rosa, CarlosCarrasco, HéctorCardona, WilsonGallardo, ClaudioEspinoza, Luis2016-07-212016-07-212009Quím. Nova vol.32 no.6 São Paulo 20090100-4042http://dx.doi.org/10.1590/S0100-40422009000600020http://repositorio.unab.cl/xmlui/handle/ria/1132Indexación: Web of Science; ScieloToxicity and antioxidant capacity of eugenol derivatives (E2 = 2-Methoxy-4-[1-propenylphenyl]acetate, E3 = 4-Allyl-2-methoxyphenylacetate, E4 = 4-Allyl-2-methoxy-4-nitrophenol, E5 = 5-Allyl-3-nitrobenzene-1,2-diol, E6 = 4-Allyl-2-methoxy-5-nitrophenyl acetate) were evaluated in order to determine the influence of the sustituents. E2-E6 were synthesized from eugenol (E1). E1 was extracted from cloves oil, and E2-E6 were obtained through acetylation and nitration reactions. Antioxidant capacity evaluated by DPPH (1, 1-Diphenyl-2-picrylhydrazil) and ORAC fluorescein demonstrated that E1 and E5 have a higher capacity and the minor toxicity evaluated by red blood cells haemolysis and the Artemia saline test. In accordance with our results, the compound's (E1-E5) use in the pharmaceutical, cosmetic and or food industries could be suggested.enEugenol derivativesAntioxidant capacityArtículo