Petermann-Rocha, FannyDiaz-Toro, FelipeTroncoso-Pantoja, ClaudiaMartínez-Sanguinetti, María AdelaLeiva-Ordoñez, Ana MaríaNazar, GabrielaConcha-Cisternas, YenyMartínez, Ximena DíazLanuza, FabianCarrasco-Marín, FernandaMartorell, MiquelRamírez-Alarcón, KarinaLabrana, Ana MaríaParra-Soto, SolangeVillagran, MarceloLasserre-Laso, NicoleCigarroa, IgorMardones, LorenaVásquez-Gómez, JaimeCelis-Morales, Carlos A.2024-04-162024-04-162024-12-06Public Health Nutrition Open AccessVolume 27, Issue 16 December 2024 Article number e913689800https://repositorio.unab.cl/handle/ria/56008Indexación: Scopus.Objective: To investigate the association between a lifestyle score and all-cause mortality in the Chilean population. Design: Prospective study. Settings: The score was based on seven modifiable behaviours: salt intake, fruit and vegetable intake, alcohol consumption, sleep duration, smoking, physical activity and sedentary behaviours. 1-point was assigned for each healthy recommendation. Points were summed to create an unweighted score from 0 (less healthy) to 7 (healthiest). According to their score, participants were then classified into: less healthy (0–2 points), moderately healthy (3–4 points) and the healthiest (5–7 points). Associations between the categories of lifestyle score and all-cause mortality were investigated using Cox proportional hazard models adjusted for confounders. Nonlinear associations were also investigated. Participants: 2706 participants from the Chilean National Health Survey 2009–2010. Results: After a median follow-up of 10·9 years, 286 (10·6 %) participants died. In the maximally adjusted model, and compared with the healthiest participants, those less healthy had 2·55 (95 % CI 1·75, 3·71) times higher mortality risk due to any cause. Similar trends were identified for the moderately healthy group. Moreover, there was a significant trend towards increasing the mortality risk when increasing unhealthy behaviours (hazard ratio model 3: 1·61 (95 % CI 1·34, 1·94)). There was no evidence of nonlinearity between the lifestyle score and all-cause mortality. Conclusion: Individuals in the less healthy lifestyle category had higher mortality risk than the healthiest group. Therefore, public health strategies should be implemented to promote adherence to a healthy lifestyle across the Chilean population.enLifestylemortalityprospective studyArtículoCC BY 4.0 DEED Attribution 4.0 International10.1017/S1368980023002598