Pezoa, DavidBlondel, Carlos J.Amaya, Fernando A.Santiviago, Carlos A.2024-11-042024-11-042023-06Polish Journal of Microbiology. Volume 72, Issue 2, Pages 215 - 219. June 20231733-1331https://repositorio.unab.cl/handle/ria/61690Indexación: ScopusSalmonella genus harbors five Type VI Secretion System (T6SS) gene clusters. The T6SS encoded in SPI-6 (T6SSSPI-6) contributes to Salmonella Typhimurium colonization of chickens and mice, while the T6SS encoded in SPI-19 (T6SSSPI-19) of Salmonella Gallinarum contributes to chicken colonization. Interestingly, the T6SSSPI-19 of Salmonella Gallinarum complemented the defect in chicken colonization of a Salmonella Typhimurium strain that lacks the T6SSSPI-6, suggesting that both T6SSs are interchangeable. Here we show that the transfer of Salmonella Gallinarum T6SSSPI-19 complemented the defect in mice colonization of a Salmonella Typhimurium ΔT6SSSPI-6 strain, indicating that both T6SSs are functionally redundant during host colonization. © 2023 David Pezoa et al., published by Sciendo.enColonizationMiceSalmonella TyphimuriumSPI-19T6SSArtículoCC BY-NC-ND 4.0 Attribution-NonCommercial-NoDerivatives 4.0 International Deed10.33073/pjm-2023-017