Situación epidemiológica del virus humano de Linfocitos T tipo I y tipo II (HTLV-I/II) en donantes de sangre de la V región de Valparaíso y la importancia de su confirmación obligatoria
Cargando...
Archivos
Fecha
2008
Profesor/a Guía
Facultad/escuela
Idioma
Título de la revista
ISSN de la revista
Título del volumen
Editor
Universidad Andrés Bello
Nombre de Curso
Licencia CC
Licencia CC
Resumen
Los virus humanos de linfocitos T tipo I (HTLV-I) y tipo II (HTLV-II) son retrovirus endémicos en
diversas zonas del mundo y algunas regiones de Sudamérica, entre ellas Chile. Estos retrovirus se
han asociado a diversas enfermedades, como el síndrome linfoproliferativo y la patología
neurológica progresiva. Estos patógenos son transmisibles por células presentes en líquidos
biológicos, transplantes de órganos y transfusiones sanguíneas infectadas.
Se investiga la totalidad de donantes de sangre entre enero de 2003 y septiembre del 2008 y sus
resultados en los test que detectan anticuerpos anti HTLV-I/II en 11 centros asistenciales de la V
región de Valparaíso para revelar la situación epidemiológica del virus. Para el desarrollo de este
estudio se clasificaron los datos en 5 grupos: número de resultados repetidamente reactivos entre
enero de 2003 y septiembre del año 2008, seroprevalencia por año correspondiente al período de
enero del año 2003 y septiembre del año 2008, por edad, género y resultados de posibles falsos
reactivos entre enero del 2005 y septiembre del año 2008, según el criterio de Alan Kitchen y
Mohamed N. El-nageh.
De un total de 120890 donantes de sangre, 751 fueron repetidamente reactivos para HTLV-I/II
constituyendo un índice de seroprevalencia de 0.6%. La seroprevalencia presenta un aumento en los
6 años evaluados siendo de 0.4% en 2003, 0.7% en 2004, 0.6% en 2005, 0.7% en 2006 y 0,6% en
2007, y hasta septiembre de 2008 presentó un 0.8%.
Es por esto que se considera un riesgo de salud pública, por lo tanto, se sugiere implementar
técnicas de tamizaje y confirmación de la infección en todos los bancos de sangre del país.
in diverse zones of the world and some regions of South America, between (among) them Chile. These retrovirus have been associated to diverse diseases, as the syndrome linfoproliferativo and the neurological progressive pathology. These pathogenic are transmissible for cells present in biological liquids, transplants of organs and blood infected transfusions. The totality of blood donors between January 2003 and September 2008 is investigated along with their results in the test that detect antibodies anti HTLV-I/II in 11 welfare centers of the V region of Valparaiso to reveal the epidemiological situation of the virus. For this study the information was divided into 5 groups: number of results repeatedly reactive between January 2003 and September 2008, seroprevalence for year corresponding to the period of January 2003 and September 2008, by age, gender and results of possible false reactive between January 2005 and September 2008, according to the criterion of Alan Kitchen and Mohamed N. El-nageh. From a total of 120890 blood donors, 751 were repeatedly reactive for HTLV-I/II constituting an index of seroprevalencia of 0.6 %. The seroprevalencia presents an increase in the 6 years evaluated being 0.4 % in 2003, 0.7 % in 2004, 0.6 % in 2005, 0.7 % in 2006 and 0,6 % in 2007, and until September 2008 it’s presented 0.8 %. This is why it is considered to be a risk of public health, and therefore, it’s suggested to implement screening techniques and confirmation of the infection in all the blood banks of the country.
in diverse zones of the world and some regions of South America, between (among) them Chile. These retrovirus have been associated to diverse diseases, as the syndrome linfoproliferativo and the neurological progressive pathology. These pathogenic are transmissible for cells present in biological liquids, transplants of organs and blood infected transfusions. The totality of blood donors between January 2003 and September 2008 is investigated along with their results in the test that detect antibodies anti HTLV-I/II in 11 welfare centers of the V region of Valparaiso to reveal the epidemiological situation of the virus. For this study the information was divided into 5 groups: number of results repeatedly reactive between January 2003 and September 2008, seroprevalence for year corresponding to the period of January 2003 and September 2008, by age, gender and results of possible false reactive between January 2005 and September 2008, according to the criterion of Alan Kitchen and Mohamed N. El-nageh. From a total of 120890 blood donors, 751 were repeatedly reactive for HTLV-I/II constituting an index of seroprevalencia of 0.6 %. The seroprevalencia presents an increase in the 6 years evaluated being 0.4 % in 2003, 0.7 % in 2004, 0.6 % in 2005, 0.7 % in 2006 and 0,6 % in 2007, and until September 2008 it’s presented 0.8 %. This is why it is considered to be a risk of public health, and therefore, it’s suggested to implement screening techniques and confirmation of the infection in all the blood banks of the country.
Notas
Tesis (Tecnología Médica)
Palabras clave
Bancos de Sangre, Retrovirus, Patologías neurológicas