• Login
    View Item 
    •   DSpace Home
    • INVESTIGACIÓN ACADÉMICA
    • Facultad de Ciencias de la Vida
    • Fac.CV - Artículos de Revista
    • View Item
    •   DSpace Home
    • INVESTIGACIÓN ACADÉMICA
    • Facultad de Ciencias de la Vida
    • Fac.CV - Artículos de Revista
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Towards the bridging of molecular genetics data across Xenopus species

    Thumbnail
    View/Open
    TEXTO COMPLETO INGLES (980.2Kb)
    Date
    2016-03
    Author
    Riadi, G.
    Ossandón, F.
    Larraín, J.
    Melo, F.
    Metadata
    Show full item record
    Abstract
    Background: The clawed African frog Xenopus laevis has been one of the main vertebrate models for studies in developmental biology. However, for genetic studies, Xenopus tropicalis has been the experimental model of choice because it shorter life cycle and due to a more tractable genome that does not result from genome duplication as in the case of X. laevis. Today, although still organized in a large number of scaffolds, nearly 85 % of X. tropicalis and 89 % of X. laevis genomes have been sequenced. There is expectation for a comparative physical map that can be used as a Rosetta Stone between X. laevis genetic studies and X. tropicalis genomic research. Results: In this work, we have mapped using coarse-grained alignment the 18 chromosomes of X. laevis, release 9.1, on the 10 reference scaffolds representing the haploid genome of X. tropicalis, release 9.0. After validating the mapping with theoretical data, and estimating reference averages of genome sequence identity, 37 to 44 % between the two species, we have carried out a synteny analysis for 2,112 orthologous genes. We found that 99.6 % of genes are in the same organization. Conclusions: Taken together, our results make possible to establish the correspondence between 62 and 65.5 % of both genomes, percentage of identity, synteny and automatic annotation of transcripts of both species, providing a new and more comprehensive tool for comparative analysis of these two species, by allowing to bridge molecular genetics data among them.
    URI
    http://repositorio.unab.cl/xmlui/handle/ria/3998
    Collections
    • Fac.CV - Artículos de Revista

    DSpace software copyright © 2002-2016  DuraSpace
    Contact Us | Send Feedback
    Theme by 
    Atmire NV
     

     

    Documentos Trabajos de TitulaciónProcedimientos de publicaciónDerecho de autorGuía para Trabajos de Titulación pre y post gradoFormulario de AutorizaciónLogo Institucional

    Browse

    All of DSpaceCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects

    My Account

    LoginRegister

    Statistics

    View Usage Statistics

    DSpace software copyright © 2002-2016  DuraSpace
    Contact Us | Send Feedback
    Theme by 
    Atmire NV