Repositorio Institucional Académico. Universidad Andrés Bello. Chile

Mostrando 1 - 1 de 1

Editorial: Host-pathogen interaction in cestodes infection
(Frontiers Media SA, 2023) Tharmalingam, Jayaraman; Brehm, Klaus; Kundu, Suman; Młocicki, Daniel; Paredes, Rodolfo
Host-pathogen interaction is a complex process specifically during infection with multicellular parasites such as cestodes. Every year, millions of people become infected, and thousands of deaths occur due to this. The World Health Organization listed many of the cestode infections under Neglected Tropical Diseases (NTDs) to address the urgent need to prevent the infection. Number of the NTDs causes millions of Disability Adjusted Life Years (DALYs) and cost billions of dollars in morbidity and mortality associated with diseases every year (Engels and Zhou, 2020). For thousands of years, tapeworms co-evolved with many of its intermediate and definite hosts (including humans) and this complicated and undermined the host response to cestode infections. The complexity of cestodiases is one of the major reasons for a sustained infection burden worldwide, even though effective treatments are available. The most serious pathological changes during cestode infections are related formation space-occupying metacestodes in diverse of the hosts vital organs and such fatal infections cause neurocysticercosis, cysticercosis, coenurosis, echinococcosis, and sparganosis. In many cases metacestodes are formed by Vesicle Fluid (VF) filled in a space occupying Vesicle Tissue (VT)