Examinando por Autor "Catalan Marin, Karen"

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    Ítem
    Synthesis of two new hemisynthetic diterpenylhydroquinones from natural iiwf-Labdanes
    (MDPI, 2009-06) Espinoza Catálan, Luis; Catalan Marin, Karen; Madrid Villegas, Alejandro; Carrasco Altamirano, Héctor; Villena García, Joan; Cuellar Fritis, Mauricio
    The synthesis and structural determination of two new diterpenylhydroquinones: 2β-acetoxy-15-phenyl-(22,25-dihydroxy)-ent-labda- 8(17),13(£)-diene (1) and 2β-hydroxy- 15-phenyl-(22,25-dihydroxy)- ent-labda-8(17),13(E)-diene is reported (2). These compounds were obtained by coupling via Electrophilic Aromatic Substitution (EAS) of 1,4-hydroquinone with primary or tertiary allyl alcohol derivatives of the natural ent- labdanes 3 and 4. With this new method, the best results were observed when mixtures of the primary alcohol derivatives 5-6 (26% yield of compound 1) and diol derivatives 9-10 (28% yield of compound 2) were used.