Examinando por Autor "Lasserre-Laso, Nicole"
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Ítem Association between a lifestyle score and all-cause mortality: a prospective analysis of the Chilean National Health Survey 2009–2010(Cambridge University Press CODEN, 2024-12-06) Petermann-Rocha, Fanny; Diaz-Toro, Felipe; Troncoso-Pantoja, Claudia; Martínez-Sanguinetti, María Adela; Leiva-Ordoñez, Ana María; Nazar, Gabriela; Concha-Cisternas, Yeny; Martínez, Ximena Díaz; Lanuza, Fabian; Carrasco-Marín, Fernanda; Martorell, Miquel; Ramírez-Alarcón, Karina; Labrana, Ana María; Parra-Soto, Solange; Villagran, Marcelo; Lasserre-Laso, Nicole; Cigarroa, Igor; Mardones, Lorena; Vásquez-Gómez, Jaime; Celis-Morales, Carlos A.Objective: To investigate the association between a lifestyle score and all-cause mortality in the Chilean population. Design: Prospective study. Settings: The score was based on seven modifiable behaviours: salt intake, fruit and vegetable intake, alcohol consumption, sleep duration, smoking, physical activity and sedentary behaviours. 1-point was assigned for each healthy recommendation. Points were summed to create an unweighted score from 0 (less healthy) to 7 (healthiest). According to their score, participants were then classified into: less healthy (0–2 points), moderately healthy (3–4 points) and the healthiest (5–7 points). Associations between the categories of lifestyle score and all-cause mortality were investigated using Cox proportional hazard models adjusted for confounders. Nonlinear associations were also investigated. Participants: 2706 participants from the Chilean National Health Survey 2009–2010. Results: After a median follow-up of 10·9 years, 286 (10·6 %) participants died. In the maximally adjusted model, and compared with the healthiest participants, those less healthy had 2·55 (95 % CI 1·75, 3·71) times higher mortality risk due to any cause. Similar trends were identified for the moderately healthy group. Moreover, there was a significant trend towards increasing the mortality risk when increasing unhealthy behaviours (hazard ratio model 3: 1·61 (95 % CI 1·34, 1·94)). There was no evidence of nonlinearity between the lifestyle score and all-cause mortality. Conclusion: Individuals in the less healthy lifestyle category had higher mortality risk than the healthiest group. Therefore, public health strategies should be implemented to promote adherence to a healthy lifestyle across the Chilean population.Ítem Frailty Index as a Predictor of Mortality in Middle-Aged and Older People: A Prospective Analysis of Chilean Adults(MDPI, 2023-01) Diaz-Toro, Felipe; Nazar, Gabriela; Troncoso, Claudia; Concha-Cisternas, Yeny; Leiva-Ordoñez, Ana Maria; Martinez-Sanguinetti, Maria Adela; Parra-Soto, Solange; Lasserre-Laso, Nicole; Cigarroa, Igor; Mardones, Lorena; Vásquez-Gómez, Jaime; Petermann-Rocha, Fanny; Diaz-Martinez, Ximena; Celis-Morales, CarlosWe aimed to investigate the association between frailty status and all-cause mortality in middle-aged and older people. We included 2661 individuals aged ≥ 35 from the Chilean National Health Survey 2009–2010. Mortality was determined through linkage with the Chilean Civil Registry and Identification. A 36-item frailty index (FI) was used to assess the frailty status. Associations between frailty status and all-cause mortality were assessed using Kaplan–Meier and Cox proportional hazard models adjusted for sociodemographic and lifestyle factors. A non-linear association was investigated using penalized cubic splines fitted in the Cox models. During an 8.9 median follow-up (interquartile range of 8.6–9.0), 308 individuals died (11.5%). Lower survival rates were observed in frail individuals compared to pre-frail and robust people (log-rank < 0.001). Compared with robust individuals, frail people had a higher mortality risk (HR: 2.35 [95% CI: 1.57 to 3.51]). Frail middle-aged individuals had a higher risk of dying independently of major risk factors. © 2023 by the authors.