Examinando por Autor "Muñoz, C."

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    Georeferenced Environmental Platform for Kindergarten Monitoring Based on Internet of Things and Websockets
    (Elsevier, 2024) Fuentes, J.; Silva, M.; Muñoz, C.; Reyes, H.; Bustamante-Encina, R.; Gatica, G.
    This project involves creating a real-time geo-referenced measurement platform for kindergartens, utilizing IoT technology and the WebSockets protocol to enhance environmental information in socially significant areas. The platform displays air quality data on a map and provides Twitter alerts for local pollution events. Tests in two kindergartens demonstrated effective data capture and transmission to a central server, achieving a 92% success rate at distances exceeding 800 meters. The platform also distinguished environmental differences between the kindergartens based on location, proving its utility in supporting parents and guardians in selecting kindergartens for their children.
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    Investigating a predicted metallicity [Fe/H] variation in the Type II Globular Cluster NGC 362
    (Oxford University Press, 2022-09-01) Vargas, C.; Villanova, S.; Geisler, D.; Muñoz, C.; Monaco, L.; O'Connell, J.; Sarajedini, Ata
    NGC 362 is a non-common Type II Galactic globular cluster, showing a complex pseudo two-colour diagram or 'chromosome map'. The clear separation of its stellar populations in the colour-magnitude diagram and the distribution of the giant stars in the chromosome map strongly suggests that NGC 362 could host stars with both cluster-nominal, as well as enhanced heavy-element abundances, and one of them could be iron. However, despite previous spectroscopic observations of NGC 362, no such iron variation has been detected. Our main goal is to confirm or disprove this result by searching for any internal variation of [Fe/H], which would give us insight into the formation and evolution of this interesting globular cluster. In this paper, we present the abundance analysis for a sample of 11 red giant branch members based on high-resolution and high S/N spectra obtained with the MIKE echelle spectrograph mounted at the Magellan-Clay telescope. HST and GAIA photometry and astrometry has been used to determine atmospheric parameters and membership. We obtained Teff, log(g), and vt for our target stars and measured the mean iron content of the sample and its dispersion with three different methods, which lead to [Fe/H]1 =-1.10±0.02, [Fe/H]2 =-1.09 ±0.01, and [Fe/H]3 =-1.10 ±0.01, while the internal dispersion turned out to be σ[ Fe/H ]1 = 0.06 ±0.01, σ[Fe/H ]2 = 0.03 ±0.01, and σ[ Fe/H ]3 = 0.05 ±0.01, respectively. The error analysis gives an internal dispersion due to observational error of 0.05 dex. Comparing the observed dispersion with the internal errors, we conclude that NGC 362 does not show any trace of an internal iron spread. © 2022 The Author(s) Published by Oxford University Press on behalf of Royal Astronomical Society.
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    Neisseria gonorrhoeae challenge increases matrix metalloproteinase-8 expression in fallopian tube explants
    (Frontiers Media, 2017-09) Juica, N.E.; Rodas, P.I.; Solar, P.; Borda, P.; Vargas, R.; Muñoz, C.; Paredes, R.; Christodoulides, M.; Velasquez, L.A.
    Background: Neisseria gonorrhoeae (Ngo) is the etiological agent of gonorrhea, a sexually transmitted infection that initially infects the female lower genital tract. In untreated women, the bacteria can ascend to the upper genital reproductive tract and infect the fallopian tube (FTs), which is associated with salpingitis and can lead to impaired FT function and infertility. The extracellular matrix (ECM) plays an important role in cell migration and differentiation in the female genital tract, and some pathogens modify the ECM to establish successful infections. The ECM is regulated by matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs), their endogenous inhibitors; MMP deregulation causes pathological conditions in a variety of tissues. Results: The aim of this work was to analyze the expression and localization of MMP-3, MMP-8, MMP-9, and TIMP-1 in FT explants during Ngo infection using real-time PCR, immunohistochemistry, zymography and ELISA. No significant variations in MMP-3, MMP-9, and TIMP-1 transcript levels were observed. In contrast, a significant increase (p < 0.05) was observed for MMP-8 expression and was accompanied by stromal immunoreactivity in infected explants. ELISA results supported these findings and showed that MMP-8 release increased upon gonococcal infection. Conclusions: Our results indicate that gonococcal infection induces increased MMP-8 expression, which might contribute to FT damage during infection. © 2017 Juica, Rodas, Solar, Borda, Vargas, Muñoz, Paredes, Christodoulides and Velasquez.