Intestinal microbiota influences non-intestinal related autoimmune diseases

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dc.contributor.authorOpazo, M.C.
dc.contributor.authorOrtega-Rocha, E.M.
dc.contributor.authorCoronado-Arrázola, I.
dc.contributor.authorBonifaz, L.C.
dc.contributor.authorBoudin, H.
dc.contributor.authorNeunlist, M.
dc.contributor.authorBueno, S.M.
dc.contributor.authorKalergis, A.M.
dc.contributor.authorRiedel, C.A.
dc.date.accessioned2018-09-24T20:07:56Z
dc.date.available2018-09-24T20:07:56Z
dc.date.issued2018-03
dc.descriptionIndexación: Scopus.es_ES
dc.description.abstractThe human body is colonized by millions of microorganisms named microbiota that interact with our tissues in a cooperative and non-pathogenic manner. These microorganisms are present in the skin, gut, nasal, oral cavities, and genital tract. In fact, it has been described that the microbiota contributes to balancing the immune system to maintain host homeostasis. The gut is a vital organ where microbiota can influence and determine the function of cells of the immune system and contributes to preserve the wellbeing of the individual. Several articles have emphasized the connection between intestinal autoimmune diseases, such as Crohn's disease with dysbiosis or an imbalance in the microbiota composition in the gut. However, little is known about the role of the microbiota in autoimmune pathologies affecting other tissues than the intestine. This article focuses on what is known about the role that gut microbiota can play in the pathogenesis of non-intestinal autoimmune diseases, such as Grave's diseases, multiple sclerosis, type-1 diabetes, systemic lupus erythematosus, psoriasis, schizophrenia, and autism spectrum disorders. Furthermore, we discuss as to how metabolites derived from bacteria could be used as potential therapies for non-intestinal autoimmune diseases. © 2018 Opazo, Ortega-Rocha, Coronado-Arrázola, Bonifaz, Boudin, Neunlist, Bueno, Kalergis and Riedel.es_ES
dc.description.urihttps://www.frontiersin.org/articles/10.3389/fmicb.2018.00432/full
dc.identifier.citationFrontiers in Microbiology, 9(MAR), art. no. 432.es_ES
dc.identifier.issn1664-302X
dc.identifier.otherDOI: 10.3389/fmicb.2018.00432
dc.identifier.urihttp://repositorio.unab.cl/xmlui/handle/ria/7044
dc.language.isoenes_ES
dc.publisherFrontiers Mediaes_ES
dc.subjectAutoimmune diseasees_ES
dc.subjectCNSes_ES
dc.subjectGutes_ES
dc.subjectMicrobiomees_ES
dc.subjectMicrobiotaes_ES
dc.subjectSkines_ES
dc.titleIntestinal microbiota influences non-intestinal related autoimmune diseaseses_ES
dc.typeArtículoes_ES
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