The Ca2+ pump inhibitor, thapsigargin, inhibits root gravitropism in Arabidopsis thaliana

dc.contributor.authorUrbina, Daniela
dc.contributor.authorSilva, Herman
dc.contributor.authorMeisel, Lee
dc.date.accessioned2014-06-03T19:19:50Z
dc.date.accessioned2016-05-24T18:45:06Z
dc.date.available2014-06-03T19:19:50Z
dc.date.available2016-05-24T18:45:06Z
dc.date.issued2006
dc.descriptionhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602006000200011&lng=es&nrm=isoes
dc.description.abstractThapsigargin, a specific inhibitor of most animal intracellular SERCA-type Ca2+ pumps present in the sarcoplasmic/endoplasmic reticulum, was originally isolated from the roots of the Mediterranean plant Thapsia gargancia L. Here, we demonstrate that this root-derived compound is capable of altering root gravitropism in Arabidopsis thaliana. Thapsigargin concentrations as low as 0.1 µM alter root gravitropism whereas under similar conditions cyclopiazonic acid does not. Furthermore, a fluorescently conjugated thapsigargin (BODIPY FL thapsigargin) suggests that target sites for thapsigargin are located in intracellular organelles in the root distal elongation zone and the root cap, regions known to regulate root gravitropism.es
dc.identifier.citationBiol. Res. v.39 n.2 Santiago 2006es
dc.identifier.issn0716-9760
dc.identifier.otherDOI: http://dx.doi.org/10.4067/S0716-97602006000200011
dc.identifier.urihttp://repositorio.unab.cl/xmlui/handle/ria/2469
dc.language.isoenes
dc.publisherSociedad de Biología de Chilees
dc.subjectArabidopsis thalianaes
dc.subjectCa2+-ATPaseses
dc.subjectCalciumes
dc.subjectGravitropismes
dc.subjectThapsigargines
dc.subjectRootes
dc.titleThe Ca2+ pump inhibitor, thapsigargin, inhibits root gravitropism in Arabidopsis thalianaes
dc.typeArtículoes
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