Genetic characterization of salmonella infantis with multiple drug resistance profiles isolated from a poultry-farm in chile

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dc.contributor.authorPardo Esté, Coral
dc.contributor.authorLorca, Diego
dc.contributor.authorCastro Severyn, Juan
dc.contributor.authorKrüger, Gabriel
dc.contributor.authorAlvarez Thon, Luis
dc.contributor.authorZepeda, Phillippi
dc.contributor.authorSulbaran Bracho, Yoelvis
dc.contributor.authorHidalgo, Alejandro
dc.contributor.authorTello, Mario
dc.contributor.authorMolina, Franck
dc.contributor.authorMolina, Laurence
dc.contributor.authorRemonsellez, Francisco
dc.contributor.authorCastro Nallar, Eduardo
dc.contributor.authorSaavedra, Claudia
dc.date.accessioned2022-08-16T22:31:00Z
dc.date.available2022-08-16T22:31:00Z
dc.date.issued2021-11
dc.descriptionIndexación : Scopuses
dc.description.abstractSalmonella comprises over 2500 serotypes and foodborne contamination associated with this pathogen remains an important health concern worldwide. During the last decade, a shift in serotype prevalence has occurred as traditionally less prevalent serotypes are increasing in frequency of infections, especially those related to poultry meat contamination. S. Infantis is one of the major emerging serotypes, and these strains commonly display antimicrobial resistance and can persist despite cleaning protocols. Thus, this work aimed to isolate S. Infantis strains from a poultry meat farm in Santiago, Chile and to characterize genetic variations present in them. We determined their genomic and phenotypic profiles at different points along the production line. The results indicate that the strains encompass 853 polymorphic sites (core-SNPs) with isolates differing from one another by 0–347 core SNPs, suggesting variation among them; however, we found discrete correlations with the source of the sample in the production line. Furthermore, the pan-genome was composed of 4854 total gene clusters of which 2618 (53.9%) corresponds to the core-genome and only 181 (3.7%) are unique genes (those present in one particular strain). This preliminary analysis will enrich the surveillance of Salmonella, yet further studies are required to assess their evolution and phylogeny. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.es
dc.description.urihttps://www.mdpi.com/2076-2607/9/11/2370
dc.identifier.citationMicroorganisms Volume 9, Issue 11November 2021 Article number 2370es
dc.identifier.doi10.3390/microorganisms9112370
dc.identifier.issn2076-2607
dc.identifier.urihttps://repositorio.unab.cl/xmlui/handle/ria/23547
dc.language.isoenes
dc.publisherMDPIes
dc.rights.licenseAtribución 4.0 Internacional (CC BY 4.0)
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/deed.es
dc.subjectGenomic; Poultryes
dc.subjectSalmonella Infantises
dc.subjectStress resistancees
dc.subjectVirulencees
dc.titleGenetic characterization of salmonella infantis with multiple drug resistance profiles isolated from a poultry-farm in chilees
dc.typeArtículoes
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