Modulation of Immune Cells as a Therapy for Cutaneous Lupus Erythematosus

Vista sencilla de ítem
dc.contributor.authorSoto, Jorge A.
dc.contributor.authorMelo-González, Felipe
dc.contributor.authorRiedel, Claudia A.
dc.contributor.authorBueno, Susan M.
dc.contributor.authorKalergis, Alexis M.
dc.date.accessioned2024-01-12T19:40:16Z
dc.date.available2024-01-12T19:40:16Z
dc.date.issued2022-09
dc.descriptionIndexación: Scopus.es
dc.description.abstractCutaneous lupus erythematosus (CLE) is an autoimmune disorder like systemic lupus erythematosus (SLE). Both SLE and CLE characterize autoantibody secretion and immune cell recruitment. In particular, CLE can be divided into three more frequent types, varying in the severity of the skin lesions they present. The role of type I IFN was shown to be one of the leading causes of the development of this pathology in the skin. Different treatments have been developed and tested against these different variants of CLE to decrease the increasing levels of CLE in humans. In this article, a literature revision discussing the similarities between SLE and CLE is carried out. In addition, new advances in understanding the development of CLE and the leading treatments being evaluated in animal models and clinical trials are reviewed.es
dc.description.urihttps://www-scopus-com.recursosbiblioteca.unab.cl/record/display.uri?eid=2-s2.0-85138401866&origin=resultslist&sort=plf-f&src=s&nlo=&nlr=&nls=&sid=7b283b2b36c596f7e0c100335c4e2fc8&sot=aff&sdt=cl&cluster=scofreetoread%2c%22all%22%2ct&sl=34&s=AF-ID%2860002636%29+AND+SUBJAREA%28CENG%29&relpos=50&citeCnt=1&searchTerm=
dc.identifier.citationInternational Journal of Molecular Sciences, Open Access, Volume 23, Issue 18 September 2022, Article number 10706es
dc.identifier.doi10.3390/ijms231810706
dc.identifier.issn16616596
dc.identifier.urihttps://repositorio.unab.cl/xmlui/handle/ria/54674
dc.language.isoenes
dc.publisherMDPIes
dc.rights.licenseCC BY 4.0 DEED Attribution 4.0 International
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectCutaneous lupus erythematosuses
dc.subjectImmune cellses
dc.subjectSystemic lupus erythematosuses
dc.subjectTreatmentses
dc.titleModulation of Immune Cells as a Therapy for Cutaneous Lupus Erythematosuses
dc.typeArtículoes
Archivos
Bloque original
Mostrando 1 - 1 de 1
Miniatura
Nombre:
Soto_J_Modulation-of-Immune-Cells-as-a-Therapy-for-Cutaneous-Lupus-Erythematosus.pdf
Tamaño:
1.1 MB
Formato:
Adobe Portable Document Format
Descripción:
TEXTO COMPLETO EN INGLÉS
Descargar
Bloque de licencias
Mostrando 1 - 1 de 1
No hay miniatura disponible
Nombre:
license.txt
Tamaño:
1.71 KB
Formato:
Item-specific license agreed upon to submission
Descripción:
Descargar
Colecciones
Fac.CV - Artículos de Revista