Efecto del β-glucano: De avena sobre el índice glicémico y carga glicémica de un suplemento nutricional edulcorado con sucralosa en adultos sanos: Un ensayo clínico aleatorizado
Archivos
Fecha
2016
Profesor/a Guía
Facultad/escuela
Idioma
en
Título de la revista
ISSN de la revista
Título del volumen
Editor
Sociedad Latinoamericana de Hipertension
Nombre de Curso
Licencia CC
Licencia CC
Resumen
Las propiedades hipoglicemiantes del β-glucano de avena
son de interés para la industria alimentaria y el área clínica,
por sus potenciales beneficios sobre la salud al disminuir la
respuesta glicémica, el nivel sérico de lipoproteínas de baja
densidad y el índice glicémico de los alimentos. Existen suplementos
nutricionales específicos para diabéticos edulcorados
con sucralosa cuyo índice glicémico y carga glicémica
aún no han sido establecidos. El efecto del β-glucano de
avena sobre el índice glicémico y carga glicémica de un suplemento
nutricional edulcorado con sucralosa, fue determinado
en 13 adultos sanos (6 hombres y 7 mujeres), quienes
consumieron aleatoriamente 4 alimentos en días distintos, de
50 g de carbohidratos cada uno: suplemento nutricional para
diabéticos (FN), suplemento nutricional con β-glucano (FN-
β), y como productos de referencia: solución glucosada (SG)
y pan blanco (PB). Se midió glicemia en ayunas y post- prandial
a los tiempos 15, 30, 45, 60, 90 y 120 min. El área bajo
la curva de glicemia resultó más baja para ambas fórmulas
(FN) 12697±993, (FN-β) 11584 ±1171, que para los productos
de referencia:(SG) 13900±1245, y (PB) 13267 ± 1557.
Los valores de índice glicémico (FN) 67,02 ± 5,69, así como
la carga glicémica resultaron intermedios y más bajos para el
suplemento con β-glucano incorporado (FN –β) 59,8 ± 6,2;
sin diferencias en la concentración de insulina, sugiriendo
que la adición del β-glucano derivado de la avena reduce la
velocidad de absorción intestinal de la glucosa, efecto que
podría estudiarse en diabéticos.
The hypoglycemic properties of oat β-glucan is of interest for the food industry and clinical area, for potencial health benefits by reducing glycemic response, serum low-density lipoprotein cholesterol, and glycemic index of meals. There are specific nutritional supplements for diabetics sweetened with sucralose whose glycemic index and glycemic load has not been established. Effect of oat β-glucan on glycemic index and glycemic load of a nutritional supplement sweetened with sucralose in healthy adults was determined in 13 healthy subjects (6 men and 7 women) old that consumed randomly 4 meals of 50 g of carbohydrates each in different days: a nutritional supplement for diabetics (FN), the nutritional supplement with β-glucan incorporated (FN-β) and two reference food, glucose solution (SG) and white bread (PB). Fasting and postprandial glycemia was measured at times 15, 30, 45, 60, 90 and 120 min. The area under the glycemia curve was lower for both formulas (FN) 12697±993, (FN-β) 11584 ±1171 than for reference products (SG) 13900±1245, y (PB) 13267 ± 1557. The values of glycemic index (GI) (FN) 67, 02 ± 5,69 and glycemic load were intermediate and more lower for the supplement with β-glucan incorporated (FN –β) 59, 8 ± 6,2, with no difference of insulin concentration . Suggesting that the addition of oat-derived β-glucan reduces the rate of intestinal absorption of glucose. This effect should be studied in diabetic.
The hypoglycemic properties of oat β-glucan is of interest for the food industry and clinical area, for potencial health benefits by reducing glycemic response, serum low-density lipoprotein cholesterol, and glycemic index of meals. There are specific nutritional supplements for diabetics sweetened with sucralose whose glycemic index and glycemic load has not been established. Effect of oat β-glucan on glycemic index and glycemic load of a nutritional supplement sweetened with sucralose in healthy adults was determined in 13 healthy subjects (6 men and 7 women) old that consumed randomly 4 meals of 50 g of carbohydrates each in different days: a nutritional supplement for diabetics (FN), the nutritional supplement with β-glucan incorporated (FN-β) and two reference food, glucose solution (SG) and white bread (PB). Fasting and postprandial glycemia was measured at times 15, 30, 45, 60, 90 and 120 min. The area under the glycemia curve was lower for both formulas (FN) 12697±993, (FN-β) 11584 ±1171 than for reference products (SG) 13900±1245, y (PB) 13267 ± 1557. The values of glycemic index (GI) (FN) 67, 02 ± 5,69 and glycemic load were intermediate and more lower for the supplement with β-glucan incorporated (FN –β) 59, 8 ± 6,2, with no difference of insulin concentration . Suggesting that the addition of oat-derived β-glucan reduces the rate of intestinal absorption of glucose. This effect should be studied in diabetic.
Notas
Indexación: Scopus; Redalyc
Palabras clave
Glycemic index, Glycemic load, Oat β-glucan, Sucralose, β-glucanos de avena, Indice glicémico, Carga glicémica, Sucralosa
Citación
Archivos Venezolanos de Farmacologia y Terapeutica. Volume 35, Issue 4, 2016, Pages 77-85