Estudio comparativo en pacientes sometidos a cirugía colorrectal con preparación mecánica exclusiva y preparación mecánica con antibióticos orales

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dc.contributor.authorOlivares M., Sebastián
dc.contributor.authorCampaña V., Gonzalo
dc.contributor.authorReadi V., Alejandro
dc.contributor.authorRodríguez G., Marcelo
dc.date.accessioned2024-11-13T17:43:45Z
dc.date.available2024-11-13T17:43:45Z
dc.date.issued2022
dc.descriptionIndexación: Scopus.
dc.description.abstractAim: To evaluate postoperative complications and clinical evolution in patients undergoing colectomies and anastomosis with two preoperative strategies, mechanical bowel preparation alone (MBP) and mechanical bowel preparation with oral antibiotics (MBP+OA). Materials and Method: Retrospective study, with defined inclusion and exclusion criteria. Variables studied: preoperative demographic characteris-tics, surgical intervention, anastomotic location, anastomotic leakage (AL), surgical site infection (SSI), postoperative intestinal transit, Clostridium difficile (CD) infection and hospital stay. Statistical analysis, bivariate and multivariate models were performed. Results: 216 patients studied, 149 were MBP group and 67 MBP+OA group. The group MBP had higher rates of AL (7.38% vs. 0%, p = 0.011). For left-sided colectomies, AL rate in both groups had a higher difference in the middle rectum, with no cases in the MBP+OA group (0% vs. 50%, p = 0.019). For right colectomies, the AL rates were similar in both groups. SSI was higher in MBP group (4.7% vs. 0%, p = 0.037). The bowel transit recovery was faster for MBP+OA group, determining less hospital stay (3.98 days vs. 6.39 days, p = 0.001). The group MBP+OA had a higher rate of CD colitis, 4.48% (p = 0.008). Discussion and Conclusion: These results suggest that preoperative oral antibiotic with mechanical bowel preparation could help to prevent anastomotic leaks in left-sided colectomies, also avoid surgical site infection, favoring the recovery of postoperative bowel transit, reducing hospital stay. The association to CD should be examined in larger studies. © 2022, Sociedad de Cirujanos de Chile. All rights reserved.
dc.description.urihttps://www.revistacirugia.cl/index.php/revistacirugia/article/view/1331
dc.identifier.citationRevista de Cirugia, Volume 74, Issue 2, Pages 157 - 164, 2022
dc.identifier.doi10.35687/s2452-454920220021331
dc.identifier.issn2452-4557
dc.identifier.urihttps://repositorio.unab.cl/handle/ria/61931
dc.language.isoes
dc.publisherSociedad de Cirujanos de Chile
dc.rights.licenseAttribution 4.0 International CC BY 4.0 Deed
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectAnastomotic leak
dc.subjectBowel preparation
dc.subjectColorectal surgery
dc.subjectOral antibiotics
dc.titleEstudio comparativo en pacientes sometidos a cirugía colorrectal con preparación mecánica exclusiva y preparación mecánica con antibióticos orales
dc.title.alternativeComplications and postoperative clinical evolution in patients undergoing colorectal surgery with mechanical preparation alone and mechanical preparation with oral antibiotics
dc.typeArtículo
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