Prevalencia y perfil de sensibilización a aeroalérgenos en 1.199 niños asmáticos: serie consecutiva de casos
| dc.contributor.author | Mallol, Javier | |
| dc.contributor.author | Raby, Pablo | |
| dc.contributor.author | Cambiazo, David | |
| dc.contributor.author | Peñaloza, César | |
| dc.contributor.author | Palma, Ricardo | |
| dc.contributor.author | de Orúe, Manuel | |
| dc.date.accessioned | 2015-10-13T18:58:02Z | |
| dc.date.accessioned | 2016-05-31T18:26:29Z | |
| dc.date.available | 2015-10-13T18:58:02Z | |
| dc.date.available | 2016-05-31T18:26:29Z | |
| dc.date.issued | 2014 | |
| dc.description | Indexación: Web of Science; Scielo. | |
| dc.description.abstract | Background: The prevalence of atopy in asthmatic children is widely variable around the world as demonstrated by large multicentric international studies. Aim: To determine the prevalence of atopy, defined as a positive reaction to one or more allergens in the skin prick test (SPT), in children with persistent asthma. Material and Methods: We studied 1,199 children (54% male), aged between 4 and 16 years with confirmed diagnosis of asthma and followed at a Department of Pediatric Respiratory Medicine, between 2006 and 2011. SPT was performed according to international recommendations using standardized aeroallergens, in the forearm. A positive reaction was defined as a wheal ≥ 3 mm to one or more allergens. Results: The overall prevalence of atopy (positive SPT) was 49.4% (95% confidence interval (CI) 46.5-52.2) and there was a significant trend towards a higher prevalence with increasing age (p < 0.01). The main allergens with positive reactions were Dermatophagoides with 24.9% (95% CI 26.7-31.9), grass 24.0% (95% CI 21.6-26.5), weeds 19.0% (95% CI 16.9-21.4), cat 17.7% (95% CI 15.4-20.2), and Alternaria with 11.0% (95% CI 9.1-13.1). Sixty five percent of positive children reacted to one or more allergens. There were no adverse reactions. Conclusions: In the southern metropolitan area of Santiago de Chile, half of children with asthma are sensitized to common aeroallergens. (Rev Med Chile 2014; 142: 567-573) Key words: Asthma; Child; Epidemiology; Hypersensitivity. | es |
| dc.identifier.citation | Rev Med Chile 2014; 142: 567-573 | es |
| dc.identifier.uri | http://repositorio.unab.cl/xmlui/handle/ria/2614 | |
| dc.language.iso | es | es |
| dc.publisher | Sociedad Médica de Santiago | es |
| dc.title | Prevalencia y perfil de sensibilización a aeroalérgenos en 1.199 niños asmáticos: serie consecutiva de casos | es |
| dc.type | Artículo | es |
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