The ferric iron uptake regulator (Fur) from the extreme acidophile Acidithiobacillus ferrooxidans

Vista sencilla de ítem
dc.contributor.authorQuatrini, R.
dc.contributor.authorLefimil, C.
dc.contributor.authorHolmes, D.
dc.contributor.authorJedlicki, E.
dc.date.accessioned2021-06-16T18:52:57Z
dc.date.available2021-06-16T18:52:57Z
dc.date.issued2005-06
dc.descriptionIndexación: Scopus.es
dc.description.abstractAcidithiobacillus ferrooxidans is a Gram-negative bacterium that lives at pH 2 in high concentrations of soluble ferrous and ferric iron, making it an interesting model for understanding the biological mechanisms of bacterial iron uptake and homeostasis in extremely acid conditions. A candidate furAF (Ferric Uptake Regulator) gene was identified in the A. ferrooxidans ATCC 23270 genome. FurAF has significant sequence similarity, including conservation of functional motifs, to known Fur orthologues and exhibits cross-reactivity to Escherichia coli Fur antiserum. The furAF gene is able to complement fur deficiency in E. coli in an iron-responsive manner. FurAF is also able to bind specifically to E. coli Fur regulatory regions (Fur boxes) and to a candidate Fur box from A. ferrooxidans, as judged by electrophoretic mobility shift assays. FurAF represses gene expression from E. coli Fur-responsive promoters fiu and fhuF when expressed at high protein levels. However, it increases gene expression from these promoters at low concentrations and possibly from other Fur-regulated promoters involved in iron-responsive oxidative stress respon.es
dc.description.urihttps://www.microbiologyresearch.org/content/journal/micro/10.1099/mic.0.27581-0
dc.identifier.citationMicrobiology, Volume 151, Issue 6, Pages 2005 - 2015, June 2005es
dc.identifier.doiDOI: 10.1099/mic.0.27581-0
dc.identifier.issn1350-0872
dc.identifier.urihttp://repositorio.unab.cl/xmlui/handle/ria/19124
dc.language.isoenes
dc.publisherMicrobiology Societyes
dc.subjectFures
dc.subjectRegulones
dc.subjectBisucaberines
dc.subjectAcidithiobacillus ferrooxidanses
dc.subjectEscherichia colies
dc.subjectNegibacteriaes
dc.subjectElectrophoretic Mobility Shift Assayes
dc.subjectAcidithiobacilluses
dc.subjectAmino Acid Motifses
dc.subjectbacterial genomees
dc.titleThe ferric iron uptake regulator (Fur) from the extreme acidophile Acidithiobacillus ferrooxidanses
dc.typeArtículoes
Archivos
Bloque original
Mostrando 1 - 1 de 1
No hay miniatura disponible
Nombre:
Quatrini_The ferric iron uptake regulator (Fur) from the extreme acidophile Acidithiobacillus ferrooxidans.pdf
Tamaño:
326.59 KB
Formato:
Adobe Portable Document Format
Descripción:
TEXTO COMPLETO EN INGLES
Descargar
Bloque de licencias
Mostrando 1 - 1 de 1
No hay miniatura disponible
Nombre:
license.txt
Tamaño:
1.71 KB
Formato:
Item-specific license agreed upon to submission
Descripción:
Descargar
Colecciones
Fac.CV - Artículos de Revista