Seasonal environmental changes regulate the expression of the histone variant macroH2A in an eurythermal fish

Vista sencilla de ítem
dc.contributor.authorPinto, R.
dc.contributor.authorIvaldi, C.
dc.contributor.authorReyes, M.
dc.contributor.authorDoyen, C.
dc.contributor.authorMietton, F.
dc.contributor.authorMongelard, F.
dc.contributor.authorAlvarez, M.
dc.contributor.authorMolina, A.
dc.contributor.authorDimitrov, S.
dc.contributor.authorKrauskopf, M.
dc.contributor.authorVera, M.
dc.contributor.authorBouvet, P.
dc.date.accessioned2021-06-18T21:32:45Z
dc.date.available2021-06-18T21:32:45Z
dc.date.issued2005-10
dc.descriptionIndexación: Scopus.es
dc.description.abstractAdaptation to cold and warm conditions requires dramatic change in gene expression. The acclimatization process of the common carp Cyprinus carpio L. in its natural habitat has been used to study how organisms respond to natural environmental changes. At the cellular level, adaptation to cold condition is accompanied by a dramatic alteration in nucleolar structure and a down regulation of the expression of ribosomal genes. We show that the enrichment of condensed chromatin in winter adapted cells is not correlated with an increase of the heterochromatin marker trimethyl and monomethyl K20H4. However, the expression of the tri methyl K4 H3 and of the variant histone macroH2A is significantly increased during the winter season together with a hypermethylation of CpG residues. Taking into account the properties of macroH2A toward chromatin structure and dynamics and its role in gene repression our data suggest that the increased expression of macroH2A and the hypermethylation of DNA which occurs upon winter-acclimatization plays a major role for the reorganization of chromatin structure and the regulation of gene expression during the physiological adaptation to a colder environment.es
dc.description.urihttps://febs.onlinelibrary.wiley.com/doi/epdf/10.1016/j.febslet.2005.09.019
dc.identifier.citationFEBS Letters, Volume 579, Issue 25, Pages 5553 - 5558, 24 October 2005es
dc.identifier.doiDOI: 10.1016/j.febslet.2005.09.019
dc.identifier.issn0014-5793
dc.identifier.urihttp://repositorio.unab.cl/xmlui/handle/ria/19141
dc.language.isoenes
dc.publisherElsevier [Former Publisher] Federation of European Biochemical Societies [Associate Organisation] Wiley [Commercial Publisher]es
dc.subjectAcclimatizationes
dc.subjectChromatines
dc.subjectHistone variantes
dc.subjectMacroH2A; Nucleoluses
dc.titleSeasonal environmental changes regulate the expression of the histone variant macroH2A in an eurythermal fishes
dc.typeArtículoes
Archivos
Bloque original
Mostrando 1 - 1 de 1
Miniatura
Nombre:
Pinto_Seasonal environmental changes regulate the expression of the histone variant macroH2A in an eurythermal fish.pdf
Tamaño:
794.94 KB
Formato:
Adobe Portable Document Format
Descripción:
TEXTO COMPLETO EN INGLES
Descargar
Bloque de licencias
Mostrando 1 - 1 de 1
No hay miniatura disponible
Nombre:
license.txt
Tamaño:
1.71 KB
Formato:
Item-specific license agreed upon to submission
Descripción:
Descargar
Colecciones
Fac.CV - Artículos de Revista