Two centuries of vaccination: historical and conceptual approach and future perspectives

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dc.contributor.authorMontero, David A.
dc.contributor.authorVidal, Roberto M.
dc.contributor.authorVelasco, Juliana
dc.contributor.authorCarreño, Leandro J.
dc.contributor.authorTorres, Juan P.
dc.contributor.authorBenachi O, Manuel A.
dc.contributor.authorTovar-Rosero, Yenifer-Yadira
dc.contributor.authorOñate, Angel A.
dc.contributor.authorO'Ryan, Miguel
dc.date.accessioned2024-07-29T22:30:40Z
dc.date.available2024-07-29T22:30:40Z
dc.date.issued2023
dc.descriptionIndexación: Scopus
dc.description.abstractOver the past two centuries, vaccines have been critical for the prevention of infectious diseases and are considered milestones in the medical and public health history. The World Health Organization estimates that vaccination currently prevents approximately 3.5–5 million deaths annually, attributed to diseases such as diphtheria, tetanus, pertussis, influenza, and measles. Vaccination has been instrumental in eradicating important pathogens, including the smallpox virus and wild poliovirus types 2 and 3. This narrative review offers a detailed journey through the history and advancements in vaccinology, tailored for healthcare workers. It traces pivotal milestones, beginning with the variolation practices in the early 17th century, the development of the first smallpox vaccine, and the continuous evolution and innovation in vaccine development up to the present day. We also briefly review immunological principles underlying vaccination, as well as the main vaccine types, with a special mention of the recently introduced mRNA vaccine technology. Additionally, we discuss the broad benefits of vaccines, including their role in reducing morbidity and mortality, and in fostering socioeconomic development in communities. Finally, we address the issue of vaccine hesitancy and discuss effective strategies to promote vaccine acceptance. Research, collaboration, and the widespread acceptance and use of vaccines are imperative for the continued success of vaccination programs in controlling and ultimately eradicating infectious diseases. Copyright © 2024 Montero, Vidal, Velasco, Carreño, Torres, Benachi O., Tovar-Rosero, Oñate and O'Ryan
dc.description.urihttps://www.frontiersin.org/journals/public-health/articles/10.3389/fpubh.2023.1326154/full
dc.identifier.citationFrontiers in Public Health. Volume 11. 2023. Article number 1326154
dc.identifier.doi10.3389/fpubh.2023.1326154
dc.identifier.issn2296-2565
dc.identifier.urihttps://repositorio.unab.cl/handle/ria/58849
dc.language.isoen
dc.publisherFrontiers Media SA
dc.rights.licenseCC BY 4.0 Attribution 4.0 International Deed
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectHealth Literacy
dc.subjectHistory of Vaccines
dc.subjectTypes of Vaccines
dc.subjectHistory of Vaccines
dc.subjectVaccine Development
dc.subjectVaccine Hesitancy
dc.subjectVaccines
dc.subjectVaccinology
dc.titleTwo centuries of vaccination: historical and conceptual approach and future perspectives
dc.typeArtículo
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