Antarctic penguins as reservoirs of diversity for avian avulaviruses

Vista sencilla de ítem
dc.contributor.authorWille, Michelle
dc.contributor.authorAban, Malet
dc.contributor.authorWang, Jing
dc.contributor.authorMoore, Nicole
dc.contributor.authorShan, Songhua
dc.contributor.authorMarshall, John
dc.contributor.authorGonzález-Acuña, Daniel
dc.contributor.authorVijaykrishna, Dhanasekaran
dc.contributor.authorButler, Jeff
dc.contributor.authorWang, Jianning
dc.contributor.authorHall, Richard
dc.contributor.authorWilliams, David T.
dc.date.accessioned2023-04-20T14:35:07Z
dc.date.available2023-04-20T14:35:07Z
dc.date.issued2019
dc.descriptionIndexación Scopuses
dc.description.abstractWild birds harbor a huge diversity of avian avulaviruses (formerly avian paramyxoviruses). Antarctic penguin species have been screened for avian avulaviruses since the 1980s and, as such, are known hosts of these viruses. In this study, we screened three penguin species from the South Shetland Islands and the Antarctic Peninsula for avian avulaviruses. We show that Adelie penguins (Pygoscelis adeliae) are hosts for four different avian avulavirus species, the recently described avian avulaviruses 17 to 19 and avian avulavirus 10-like, never before isolated in Antarctica. A total of 24 viruses were isolated and sequenced; avian avulavirus 17 was the most common, and phylogenetic analysis demonstrated patterns of occurrence, with different genetic clusters corresponding to penguin age and location. Following infection in specific-pathogen-free (SPF) chickens, all four avian avulavirus species were shed from the oral cavity for up to 7 days postinfection. There was limited shedding from the cloaca in a proportion of infected chickens, and all but one bird seroconverted by day 21. No clinical signs were observed. Taken together, we propose that penguin species, including Antarctic penguins, may be the central reservoir for a diversity of avian avulavirus species and that these viruses have the potential to infect other avian hosts. IMPORTANCE Approximately 99% of all viruses are still to be described, and in our changing world, any one of these unknown viruses could potentially expand their host range and cause epidemic disease in wildlife, agricultural animals, or humans. Avian avulavirus 1 causes outbreaks in wild birds and poultry and is thus well described. However, for many avulavirus species, only a single specimen has been described, and their viral ecology and epidemiology are unknown. Through the detection of avian avulaviruses in penguins from Antarctica, we have been able to expand upon our understanding of three avian avulavirus species (avian avulaviruses 17 to 19) and report a potentially novel avulavirus species. Importantly, we show that penguins appear to play a key role in the epidemiology of avian avulaviruses, and we encourage additional sampling of this avian group.es
dc.identifier.citationJournal of Virology Volume 93, Issue 11 2019 Article number e0027119es
dc.identifier.doi10.1128/JVI.00271-19en
dc.identifier.issn0022-538X
dc.identifier.urihttps://repositorio.unab.cl/xmlui/handle/ria/48790
dc.language.isoenes
dc.publisherJournal of Virologyes
dc.rights.licenseAttribution 4.0 International (CC BY 4.0)en
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/en
dc.subjectAdelie penguines
dc.subjectAntarcticaes
dc.subjectAvian avulaviruses
dc.subjectAvian paramyxoviruses
dc.subjectDisease ecologyes
dc.subjectPenguines
dc.subjectSphenisciformeses
dc.titleAntarctic penguins as reservoirs of diversity for avian avulaviruseses
dc.typeArtículoes
Archivos
Bloque original
Mostrando 1 - 1 de 1
Miniatura
Nombre:
Antarctic-penguins-as-reservoirs-of-diversity-for-avian-avulavirusesJournal-of-Virology.pdf
Tamaño:
648.15 KB
Formato:
Adobe Portable Document Format
Descripción:
TEXTO COMPLETO EN INGLÉS
Descargar
Bloque de licencias
Mostrando 1 - 1 de 1
No hay miniatura disponible
Nombre:
license.txt
Tamaño:
1.71 KB
Formato:
Item-specific license agreed upon to submission
Descripción:
Descargar
Colecciones
Fac.CV - Artículos de Revista