A Modeled High-Density Fed-Batch Culture Improves Biomass Growth and β-Glucans Accumulation in Microchloropsis salina

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dc.contributor.authorOcaranza, Darío
dc.contributor.authorBalic, Iván
dc.contributor.authorBruna, Tamara
dc.contributor.authorMoreno, Ignacio
dc.contributor.authorDíaz, Oscar
dc.contributor.authorMoreno, Adrián A.
dc.contributor.authorCaro, Nelson
dc.date.accessioned2023-07-19T16:42:35Z
dc.date.available2023-07-19T16:42:35Z
dc.date.issued2022-12
dc.descriptionIndexación Scopuses
dc.description.abstractAlgae and microalgae are used as a source of different biomolecules, such as lipids and carbohydrates. Among carbohydrates, polysaccharides, such as β-glucans, are important for their application as antioxidants, antisepsis, and immunomodulators. In the present work, the β-glucans production potential of Microchloropsis salina was assessed using two different culture conditions: a high-density batch and a modeled high-density fed-batch. From the biochemical parameters determined from these two cultures conditions, it was possible to establish that the modeled high density fed-batch culture improves the biomass growth. It was possible to obtain a biomass pro ductivity equal to 8.00 × 10−2 ± 2.00 × 10−3 g/(L × day), while the batch condition reached 5.13 × 10−2 ± 4.00 × 10−4 g/(L × day). The same phenomenon was observed when analyzing the β-glucans accumulation, reaching volumetric productivity equal to 5.96 × 10−3 ± 2.00 × 10−4 g of product/(L × day) against the 4.10 × 10−3 ± 2.00 × 10−4 g of product/(L × day) obtained in batch conditions. These data establish a baseline condition to optimize and significantly increase β-glucan productivity, as well as biomass, adding a new and productive source of this polymer, and integrating its use in potential applications in the human and animal nutraceutical industry.es
dc.identifier.citationPlants Volume 11, Issue 23 December 2022 Article number 3229es
dc.identifier.doi10.3390/plants11233229en
dc.identifier.issn2223-7747
dc.identifier.urihttps://repositorio.unab.cl/xmlui/handle/ria/51788
dc.language.isoenes
dc.publisherPlantses
dc.rights.licenseAttribution 4.0 International (CC BY 4.0)en
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/en
dc.subjectbiomasses
dc.subjectfed-batches
dc.subjectmicroalgaees
dc.subjectMicrochloropsis salinaes
dc.titleA Modeled High-Density Fed-Batch Culture Improves Biomass Growth and β-Glucans Accumulation in Microchloropsis salinaes
dc.typeArtículoes
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