Anatomy of corpus callosum in prenatally malnourished rats

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dc.contributor.authorOlivares, Ricardo
dc.contributor.authorMorgan, Carlos
dc.contributor.authorPérez, Hernan
dc.contributor.authorHernandez, Alejandro
dc.contributor.authorAboitiz, Francisco
dc.contributor.authorSoto-Moyano, Ruben
dc.contributor.authorGil, Julio
dc.contributor.authorOrtiz, Alexis
dc.contributor.authorFlores, Osvaldo
dc.contributor.authorGimeno, Miguel
dc.contributor.authorLaborda, Jesús
dc.date.accessioned2014-05-12T13:53:55Z
dc.date.accessioned2016-05-26T20:56:34Z
dc.date.available2014-05-12T13:53:55Z
dc.date.available2016-05-26T20:56:34Z
dc.date.issued2012
dc.descriptionIndexación: Web of Science; Scieloes
dc.description.abstractThe effect of prenatal malnutrition on the anatomy of the corpus callosum was assessed in adult rats (45-52 days old). In the prenatally malnourished animals we observed a significant reduction of the corpus callosum total area, partial areas, and perimeter, as compared with normal animals. In addition, the splenium of corpus callosum (posterior fifth) showed a significant decrease of fiber diameters in the myelinated fibers without changing density. There was also a significant decrease in diameter and a significant increase in density of unmyelinated fibers. Measurements of perimeter's fractal dimensions from sagittal sections of the brain and corpus callosum did not show significant differences between malnourished and control animals. These findings indicate that cortico-cortical connections are vulnerable to the prenatal malnutrition, and suggest this may affect interhemispheric conduction velocity, particulary in visual connections (splenium).es
dc.description.urihttp://ref.scielo.org/nph4s4
dc.identifier.citationBiol. Res. vol.45 no.1 Santiago 2012es
dc.identifier.issn0716-9760
dc.identifier.otherDOI: http://dx.doi.org/10.4067/S0716-97602012000100012
dc.identifier.urihttp://repositorio.unab.cl/xmlui/handle/ria/2454
dc.language.isoenes
dc.publisherSociedad de Biología de Chilees
dc.subjectCorpus callosumes
dc.subjectPrenatal malnutritiones
dc.subjectRates
dc.subjectSpleniumes
dc.titleAnatomy of corpus callosum in prenatally malnourished ratses
dc.typeArtículoes
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