Synthesis and DPPH radical scavenging activity of prenylated phenol derivatives

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dc.contributor.authorOsorio, Mauricio
dc.contributor.authorAravena, Jacqueline
dc.contributor.authorVergara, Alejandra
dc.contributor.authorTaborga, Lautaro
dc.contributor.authorBaeza, Evelyn
dc.contributor.authorCatalán, Karen
dc.contributor.authorGonzález, Cesar
dc.contributor.authorCarvajal, Marcela
dc.contributor.authorCarrasco, Héctor
dc.contributor.authorEspinoza, Luis
dc.date.accessioned2023-07-24T20:19:28Z
dc.date.available2023-07-24T20:19:28Z
dc.date.issued2012-01
dc.descriptionIndexación: Scopuses
dc.description.abstractThe synthesis of twenty six prenylated phenols derivatives is reported. These compounds were obtained under mild conditions via Electrophilic Aromatic Substitution (EAS) coupling reactions between phenol derivatives containing electron-donor subtituents and 3-methyl-2-buten-1-ol using BF 3·OEt 2. Dialkylations were also produced with this method. The formation of a chroman ring by intramolecular cyclization between a sp 2 carbon from the prenyl group with the hydroxyl substituent in the ortho position occurred with some phenols. All the synthesized compounds were evaluated as antioxidants according to a DPPH radical scavenging activity assay. IC 50 values of five synthesized compounds indicated they were as good antioxidants as Trolox™. © 2012 by the authors.es
dc.description.urihttps://www.mdpi.com/1420-3049/17/1/556
dc.identifier.citationMolecules Volume 17, Issue 1, Pages 556 - 570January 2012es
dc.identifier.doi10.3390/molecules17010556
dc.identifier.issn1420-3049
dc.identifier.urihttps://repositorio.unab.cl/xmlui/handle/ria/51934
dc.language.isoenes
dc.publisherMDPIes
dc.rights.licenseAttribution 3.0 Unported (CC BY 3.0)
dc.rights.urihttps://creativecommons.org/licenses/by/3.0/
dc.subjectElectrophilic aromatic substitutiones
dc.subjectPrenylated phenolses
dc.subjectRadical scavenging activityes
dc.titleSynthesis and DPPH radical scavenging activity of prenylated phenol derivativeses
dc.typeArtículoes
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