Adsorción extracorpórea de citoquinas en el tratamiento del shock séptico refractario. Casos clínicos

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dc.contributor.authorRathkamp, Mario
dc.contributor.authorTomicic, Vinko
dc.contributor.authorCornejo, Juan
dc.contributor.authorCruz, Pablo
dc.date.accessioned2022-08-01T21:08:34Z
dc.date.available2022-08-01T21:08:34Z
dc.date.issued2018-06
dc.descriptionIndexación Scopuses
dc.description.abstractIf Septic shock (SS) evolves to refractory SS, mortality could reach 90%, despite giving an optimal treatment. Nowadays, extracorporeal devices which adsorb inflammatory cytokines are available, reducing the systemic inflammatory response syndrome. These devices can be used with continuous renal replacement therapy or conventional hemodialysis. We report two diabetic females aged 50 and 58 years, who underwent a total colectomy and amputation of diabetic foot and who developed a SS with high requirements of vasoactive drugs (norepinephrine and adrenaline) to maintain a mean arterial pressure about 60 mmHg. Both were subjected to hemodialysis, connected to a cytokine hemadsorption device. The most important finding was the progressive reduction of vasopressor doses, effect that was observed nine hours after the beginning of the hemadsorption and lasted until its removal at 26 hours. Both patients survived. © 2018, Sociedad Medica de Santiago. All rights reserved.es
dc.description.abstractIf Septic shock (SS) evolves to refractory SS, mortality could reach 90%, despite giving an optimal treatment. Nowadays, extracorporeal devices which adsorb inflammatory cytokines are available, reducing the systemic inflammatory response syndrome. These devices can be used with continuous renal replacement therapy or conventional hemodialysis. We report two diabetic females aged 50 and 58 years, who underwent a total colectomy and amputation of diabetic foot and who developed a SS with high requirements of vasoactive drugs (norepinephrine and adrenaline) to maintain a mean arterial pressure about 60 mmHg. Both were subjected to hemodialysis, connected to a cytokine hemadsorption device. The most important finding was the progressive reduction of vasopressor doses, effect that was observed nine hours after the beginning of the hemadsorption and lasted until its removal at 26 hours. Both patients survived.
dc.description.urihttps://www-scielo-cl.recursosbiblioteca.unab.cl/scielo.php?script=sci_arttext&pid=S0034-98872018000600796&lng=en&nrm=iso&tlng=en
dc.identifier.citationRevista Medica de Chile Volume 146, Issue 6, Pages 796 - 801June 2018es
dc.identifier.doi10.4067/s0034-98872018000600796
dc.identifier.issn00349887
dc.identifier.urihttps://repositorio.unab.cl/xmlui/handle/ria/23395
dc.language.isoeses
dc.publisherSociedad Medica de Santiagoes
dc.subjectRenal Replacement Therapyes
dc.subjectContinuous Hemofiltrationes
dc.subjectAcute Kidney Injuryes
dc.subjectCatecholamineses
dc.subjectCytokineses
dc.subjectHemadsorptiones
dc.subjectSeptices
dc.subjectShockes
dc.titleAdsorción extracorpórea de citoquinas en el tratamiento del shock séptico refractario. Casos clínicoses
dc.title.alternativeExtracorporeal cytokine hemadsorption for the treatment of refractory septic shock. Report of two caseses
dc.typeArtículoes
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