The Role of Specialized Pro-Resolving Lipid Mediators in Inflammation-Induced Carcinogenesis

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dc.contributor.authorTorres, Wheeler
dc.contributor.authorPérez, José Luis
dc.contributor.authorDíaz, María P.
dc.contributor.authorD’Marco, Luis
dc.contributor.authorCheca-Ros, Ana
dc.contributor.authorCarrasquero, Rubén
dc.contributor.authorAngarita, Lissé
dc.contributor.authorGómez, Yosselin
dc.contributor.authorChacín, Maricarmen
dc.contributor.authorRamírez, Paola
dc.contributor.authorVillasmil, Nelson
dc.contributor.authorDurán-Agüero, Samuel
dc.date.accessioned2023-10-17T12:49:09Z
dc.date.available2023-10-17T12:49:09Z
dc.date.issued2023-08
dc.descriptionIndexación: Scopus.es
dc.description.abstractCancer is a process involving cell mutation, increased proliferation, invasion, and metastasis. Over the years, this condition has represented one of the most concerning health problems worldwide due to its significant morbidity and mortality. At present, the incidence of cancer continues to grow exponentially. Thus, it is imperative to open new avenues in cancer research to understand the molecular changes driving DNA transformation, cell-to-cell interaction derangements, and immune system surveillance decay. In this regard, evidence supports the relationship between chronic inflammation and cancer. In light of this, a group of bioactive lipids derived from polyunsaturated fatty acids (PUFAs) may have a position as novel anti-inflammatory molecules known as the specialized pro-resolving mediators (SPMs), a group of pro-resolutive inflammation agents that could improve the anti-tumor immunity. These molecules have the potential role of chemopreventive and therapeutic agents for various cancer types, and their effects have been documented in the scientific literature. Thus, this review objective centers around understanding the effect of SPMs on carcinogenesis and their potential therapeutic effect.es
dc.description.urihttps://www-scopus-com.recursosbiblioteca.unab.cl/record/display.uri?eid=2-s2.0-85169099183&origin=resultslist&sort=plf-f&src=s&nlo=&nlr=&nls=&sid=8e3bb3fa7474c95002caaca502e35695&sot=aff&sdt=aff&sl=61&s=AF-ID%28%22Universidad+Andr%c3%a9s+Bello%22+60002636%29+AND+SUBJAREA%28BIOC%29&relpos=20&citeCnt=0&searchTerm=
dc.identifier.citationInternational Journal of Molecular Sciences Open Access Volume 24, Issue 16 August 2023 Article number 12623es
dc.identifier.doi10.3390/ijms241612623
dc.identifier.issn16616596
dc.identifier.urihttps://repositorio.unab.cl/xmlui/handle/ria/53476
dc.language.isoenes
dc.publisherMDPIes
dc.rights.licenseCC BY 4.0 DEED
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectBioactive lipidses
dc.subjectCánceres
dc.subjectCarcinogenesises
dc.subjectChronic inflammationes
dc.subjectPolyunsaturated fatty acidses
dc.subjectSpecialized pro-resolving lipid mediatorses
dc.titleThe Role of Specialized Pro-Resolving Lipid Mediators in Inflammation-Induced Carcinogenesises
dc.typeArtículoes
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