Editorial: Pathway, Genetic and Process Engineering of Microbes for Biopolymer Synthesis

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Date
2020-12
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Facultad/escuela
Idioma
en
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Publisher
Frontiers Media S.A.
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Abstract
Together with the climate crisis, the heavy accumulation in oceans and soils of persistent pollutants, like polycyclic aromatics hydrocarbons and synthetic plastics, are the main drivers to impact nature and threaten human survival. It is particularly striking that most industrial polymers still originate from petrochemical sources—nearly 99% of the overall worldwide production. The result is materials that remain intact for centuries once deposited in the environment. Relying on non-renewable fossil chemicals limits our ability to establish a circular economy that promises to curb current emissions and contribute moderately to the global carbon cycle without surpassing its carrying capacity. For decades, commercial biopolymers have also been produced by microbial fermentation since nature has endowed many bacteria from urban sites to extreme environments (Orellana-Saez et al., 2019) with the enzymatic machinery to assemble these macromolecules. Despite the rapid pace of innovation, microbial biopolymers are still expensive to synthesize because the generally oxygen-intensive fermentation processes, downstream processing, and carbon feedstock cost boost production expenses (Oliveira et al., 2020). The biopolymers must additionally possess specific mechanical and physical properties to be processed industrially into products with a variety of applications (Moradali and Rehm, 2020).
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Keywords
Polyhydroxyalkanoates, Cupriavidus Necator, Burkholderia Sacchari, Succinic and lactic acid, Metabolic engineering
Citation
Frontiers in Bioengineering and Biotechnology, Open Access, Volume 823 December 2020 Article number 618383
DOI
10.3389/fbioe.2020.618383
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