Advanced glycation end products: New clinical and molecular perspectives

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dc.contributor.authorSalazar, Juan
dc.contributor.authorNavarro, Carla
dc.contributor.authorOrtega, Ángel
dc.contributor.authorNava, Manuel
dc.contributor.authorMorillo, Daniela
dc.contributor.authorTorres, Wheeler
dc.contributor.authorHernández, Marlon
dc.contributor.authorCabrera, Mayela
dc.contributor.authorAngarita, Lissé
dc.contributor.authorOrtiz, Rina
dc.contributor.authorChacín, Maricarmen
dc.contributor.authorD’marco, Luis
dc.contributor.authorBermúdez, Valmore
dc.date.accessioned2024-04-16T17:55:38Z
dc.date.available2024-04-16T17:55:38Z
dc.date.issued2021-07-02
dc.descriptionINDEXACIÓN: SCOPUS.
dc.description.abstractDiabetes mellitus (DM) is considered one of the most massive epidemics of the twenty-first century due to its high mortality rates caused mainly due to its complications; therefore, the early identification of such complications becomes a race against time to establish a prompt diag-nosis. The research of complications of DM over the years has allowed the development of numer-ous alternatives for diagnosis. Among these emerge the quantification of advanced glycation end products (AGEs) given their increased levels due to chronic hyperglycemia, while also being related to the induction of different stress-associated cellular responses and proinflammatory mechanisms involved in the progression of chronic complications of DM. Additionally, the investigation for more valuable and safe techniques has led to developing a newer, noninvasive, and effective tool, termed skin fluorescence (SAF). Hence, this study aimed to establish an update about the molecular mechanisms induced by AGEs during the evolution of chronic complications of DM and describe the newer measurement techniques available, highlighting SAF as a possible tool to measure the risk of developing DM chronic complications. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.
dc.identifier.citationInternational Journal of Environmental Research and Public Health, Volume 18, Issue 14, 2 July 2021, Article number 7236
dc.identifier.doi10.3390/ijerph18147236
dc.identifier.issn1661-7827
dc.identifier.urihttps://repositorio.unab.cl/handle/ria/56034
dc.language.isoen
dc.publisherMDPI
dc.rights.licenseCC BY 4.0 DEED Atribución 4.0 Internacional
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/deed.es
dc.subjectAdvanced glycation end products
dc.subjectChronic complications
dc.subjectDiabetes mellitus
dc.subjectSkin fluorescence
dc.titleAdvanced glycation end products: New clinical and molecular perspectives
dc.typeArtículo
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