Antifungal activity of eugenol derivatives against Botrytis cinerea

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dc.contributor.authorOlea, Andrés F.
dc.contributor.authorBravo, Angelica
dc.contributor.authorMartínez, Rolando
dc.contributor.authorThomas, Mario
dc.contributor.authorSedan, Claudia
dc.contributor.authorEspinoza, Luis
dc.contributor.authorZambrano, Elisabeth
dc.contributor.authorCarvajal, Denisse
dc.contributor.authorSilva-Moreno, Evelyn
dc.contributor.authorCarrasco, Héctor
dc.date.accessioned2023-04-05T17:55:21Z
dc.date.available2023-04-05T17:55:21Z
dc.date.issued2019-03
dc.descriptionIndexación: Scopuses
dc.description.abstractBotrytis cinerea is a worldwide spread fungus that causes the grey mold disease, which is considered the most important factor in postharvest losses in fresh fruit crops. Consequently, the control of gray mold is a matter of current and relevant interest for agricultural industries. In this work, a series of phenylpropanoids derived from eugenol were synthesized and characterized. Their effects on the mycelial growth of a virulent and multi-resistant isolate of B. cinerea (PN2) have been evaluated and IC50 values for the most active compounds range between 31–95 ppm. The antifungal activity exhibited by these compounds is strongly related to their chemical structure, i.e., increasing activity has been obtained by isomerization of the double bond or introduction of a nitro group on the aromatic ring. Based on the relationship between the fungicide activities and chemical structure, a mechanism of action is proposed. Finally, the activity of these compounds is higher than that reported for the commercial fungicide BC-1000 that is currently employed to combat this disease. Thus, our results suggest that these compounds are potential candidates to be used in the design of new and effective control with inspired natural compounds of this pathogen. © 2019 by the authors.es
dc.description.urihttps://www.mdpi.com/1420-3049/24/7/1239
dc.identifier.citationMolecules Volume 24, Issue 729 March 2019 Article number 1239es
dc.identifier.doi10.3390/molecules24071239
dc.identifier.issn1420-3049
dc.identifier.urihttps://repositorio.unab.cl/xmlui/handle/ria/48256
dc.language.isoenes
dc.publisherMDPIes
dc.rights.licenseAtribución 4.0 Internacional (CC BY 4.0)
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/deed.es
dc.subjectBotrytis cinereaes
dc.subjectChemical fungicideses
dc.subjectEugenol; Mycelial growthes
dc.subjectReactive oxygen specieses
dc.subjectResistant isolatees
dc.titleAntifungal activity of eugenol derivatives against Botrytis cinereaes
dc.typeArtículoes
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