Adsorción extracorpórea de citoquinas en el tratamiento del shock séptico refractario. Casos clínicos
Cargando...
Archivos
Fecha
2018-06
Autores
Profesor/a Guía
Facultad/escuela
Idioma
en
Título de la revista
ISSN de la revista
Título del volumen
Editor
Sociedad Medica de Santiago
Nombre de Curso
Licencia CC
Licencia CC
Resumen
If Septic shock (SS) evolves to refractory SS, mortality could reach 90%, despite giving an optimal treatment. Nowadays, extracorporeal devices which adsorb inflammatory cytokines are available, reducing the systemic inflammatory response syndrome. These devices can be used with continuous renal replacement therapy or conventional hemodialysis. We report two diabetic females aged 50 and 58 years, who underwent a total colectomy and amputation of diabetic foot and who developed a SS with high requirements of vasoactive drugs (norepinephrine and adrenaline) to maintain a mean arterial pressure about 60 mmHg. Both were subjected to hemodialysis, connected to a cytokine hemadsorption device. The most important finding was the progressive reduction of vasopressor doses, effect that was observed nine hours after the beginning of the hemadsorption and lasted until its removal at 26 hours. Both patients survived. © 2018, Sociedad Medica de Santiago. All rights reserved.
Notas
Indexación: Scopus.
Palabras clave
Catecholamines, Cytokines, Hemadsorption, Septic, Shock
Citación
Revista Medica de Chile, 146(6), pp. 796-801.