Superior vena cava syndrome due to a leiomyosarcoma of the anterior mediastinum: a case report and literature overview

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dc.contributor.authorLabarca, E.
dc.contributor.authorZapico, A.
dc.contributor.authorRíos, B.
dc.contributor.authorMartinez, F.
dc.contributor.authorSantamarina, M.
dc.date.accessioned2023-07-05T20:23:08Z
dc.date.available2023-07-05T20:23:08Z
dc.date.issued2014
dc.descriptionIndexación Scopus.es
dc.description.abstractINTRODUCTION: Leiomyosarcomas are an infrequent cause of malignant superior vena cava syndrome (VCS). PRESENTATION OF CASE: A 51-year old male patient was admitted for a three-day history of dyspnoea, dysphagia and erythema of the head and neck. Computed tomography and magnetic resonance imaging showed a lesion arising on the anterior mediastinum, which was in close proximity with a thrombus in the superior vena cava. Surgical excision was performed, including open resection of the primary tumour and an atrio-innominate vein bypass with 8-mm polytetrafluoroethylene (PTFE). Histology confirmed a leiomyosarcoma and postoperative radiotherapy sessions were performed. Due to evidence of enlarge ment of the thrombus, a second intervention was undertaken. In this procedure, a remainder of the primary tumour was resected and the superior vena cava reconstructed with an autologous pericardium patch. The patient recovered satisfactorily and was discharged on the seventh postoperative day, with no evidence for relapse after 10 months of follow-up. DISCUSSION: Leiomyosarcomas comprise less than 2% of the tumours of the mediastinum and are a rare cause of paraneoplastic VCS. Male patients in their sixties are most commonly affected. Relapses seem to be common, and thus a careful follow-up is often recommended. CONCLUSION: In spite of the limited data on the management of thoracic leiomyosarcomas, surgery is currently considered the mainstay of treatment. © 2014 The Authors. Published by Elsevier Ltd. on behalf of Surgical Associates Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/).es
dc.description.urihttps://www-clinicalkey-es.recursosbiblioteca.unab.cl/#!/content/playContent/1-s2.0-S2210261214002843?returnurl=https:%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2210261214002843%3Fshowall%3Dtrue&referrer=https:%2F%2Flogin.recursosbiblioteca.unab.cl%2F
dc.identifier.citationInternational Journal of Surgery Case Reports. Volume 5, Issue 12, Pages 984 - 987. 2014es
dc.identifier.doi10.1016/j.ijscr.2014.10.036
dc.identifier.issn2210-2612
dc.identifier.urihttps://repositorio.unab.cl/xmlui/handle/ria/51416
dc.language.isoenes
dc.publisherElsevier Ltdes
dc.rights.licenseAtribution 4.0 International (CC BY 4.0)
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/deed.es
dc.subjectSuperior Vena Cava Syndromees
dc.subjectLeiomyosarcomaes
dc.subjectVascular Neoplasmses
dc.titleSuperior vena cava syndrome due to a leiomyosarcoma of the anterior mediastinum: a case report and literature overviewes
dc.typeArtículoes
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