Glycemic index, glycemic load and insulin response of two formulas of isoglucose with different sweeteners and dietary fiber in healthy adults and type-2 diabetes

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dc.contributor.authorAngarita Dávila, Lissé Chiquinquirá
dc.contributor.authorLópez Miranda, José
dc.contributor.authorAparicio Camargo, Daniel
dc.contributor.authorParra Zuleta, Karla
dc.contributor.authorUzcátegui González, María
dc.contributor.authorCéspedes Nava, Virginia
dc.contributor.authorDurán Agüero, Samuel
dc.contributor.authorReyna Villasmil, Nadia
dc.date.accessioned2024-09-16T16:47:55Z
dc.date.available2024-09-16T16:47:55Z
dc.date.issued2017
dc.descriptionIndexación: Scopus
dc.description.abstractObjective: The aim of this study is to compare the glycemic index (GI) and glycemic load (GL) of two formulas with the same glucose content with different sweeteners and dietary fiber for diabetics in healthy adults and in patients with type-2 diabetes (DM2). Methodology: In this randomized, double-blind crossover research, eleven healthy people and six with DM2 consumed two enteral formulas, Glucerna SR®, Laboratorios Abbott C.A. (GF) and Enterex Diabetic®, Victus C.A. (EF), sweetened with fructose y sucralose, with 1.2 and 1.3 g/100 ml of fiber source respectively (four times). Additionally, they consumed glucose solution once, obtaining blood samples at 0, 15, 30, 45, 60, 90 and 120 min for controls; in the diabetics, minutes 150 and 180 were added for measuring blood glucose, basal and postprandial insulin after two and three hours. Results: The incremental area under the curve (IAUC) was lower for the formulas rather than for SG. In the healthy controls was 12,857 ± 422 for EF and 11,601 ± 272 for GF (p < 0.014). In diabetics, this curve reduced for GF (28,656 ± 123) compared to EF (29,855 ± 496) (p < 0.01). The IG resulted in 58.07 ± 8.4 and 60.7 ± 2 for GF and EF, respectively, in the controls, and 65.16 ± 0.2 and 68.06 ± 1 in diabetics, without significant differences, as well as in post-prandial insulin. Conclusions: The GI and the GL of the two formulas resulted in an intermediate value in both groups, with a glycemic profile inferior to SG. No significant differences were observed regarding insulin behavior, showing that the absorption rate of carbohydrates in these formulas is slower, with a lower glycemic impact than the pattern product; thus, making its indication acceptable for the diabetic patient. © 2017, Grupo Aula Medica S.A. All rights reserved.
dc.description.urihttps://pubmed.ncbi.nlm.nih.gov/28627186/
dc.identifier.citationNutricion Hospitalaria Volume 34, Issue 3, Pages 532 - 5392017
dc.identifier.doi10.20960/nh.654
dc.identifier.issn0212-1611
dc.identifier.urihttps://repositorio.unab.cl/handle/ria/60238
dc.language.isoen
dc.publisherGrupo Aula Medica S.A.
dc.rights.licenseAtribución/Reconocimiento-NoComercial-CompartirIgual 4.0 Internacional CC BY-NC-SA 4.0 Deed
dc.rights.urihttps://creativecommons.org/licenses/by-nc-sa/4.0/deed.es
dc.subjectDiabetes
dc.subjectFiber
dc.subjectFormulas
dc.subjectSweeteners
dc.titleGlycemic index, glycemic load and insulin response of two formulas of isoglucose with different sweeteners and dietary fiber in healthy adults and type-2 diabetes
dc.title.alternative[Índice glicémico, carga glicémica e insulina posprandial a dos fórmulas isoglucídicas con distintos edulcorantes y fibra en adultos sanos y diabéticos tipo 2]
dc.typeArtículo
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