Pharmaco-invasive approach in the management of acute myocardial infarction. Analysis of 144 cases

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dc.contributor.authorHameau, René D.
dc.contributor.authorBlacud, Ricardo M.
dc.contributor.authorFanta, Mario A.
dc.contributor.authorAlvarado, Cristobal L.
dc.contributor.authorHameau, Cristobal D.
dc.contributor.authorOlmos, Alfonso C.
dc.contributor.authorPérez, Osvaldo P.
dc.date.accessioned2024-04-08T17:19:24Z
dc.date.available2024-04-08T17:19:24Z
dc.date.issued2022-12
dc.descriptionIndexación: Scopus.
dc.description.abstractBackground: In those patients who do not have timely access to primary angioplasty, the pharmaco-invasive approach, that is, the use of thrombolysis as a bridging measure prior to the coronary angiography, is a safe alternative. Aim: To describe the features of patients with an acute ST-elevation myocardial infarction (STEMI) treated with a pharmaco-invasive strategy. Material and Methods: Descriptive observational study of 144 patients with mean age of 46 years with STEMI who received a dose of thrombolytic prior to their referral for primary angioplasty at a public hospital between 2018 and 2021. Results: There were no differences the clinical presentation according to the Killip score at admission between thrombolyzed and non-thrombolyzed patients (p = ns). Fifty-three percent of non-thrombolyzed patients were admitted with an occluded vessel (TIMI 0) compared with 27% of thrombolyzed patients (p < 0.001). The thrombolyzed group required significantly less use of thromboaspiration (3.5 and 8.4% respectively; p = 0.014). Despite this, 91 and 92% of non-thrombolyzed and thrombolyzed patients achieved a post-angioplasty TIMI 3 flow. Long-term survival was 91 and 86% in thrombolyzed and non-thrombolyzed patients, respectively (p = ns). Conclusions: The pharmaco-invasive strategy is a safe alternative when compared to primary angioplasty in centers that don`t have timely access to Interventional Cardiology. © 2022 Sociedad Medica de Santiago. All rights reserved.
dc.description.urihttps://www-scielo-cl.recursosbiblioteca.unab.cl/scielo.php?script=sci_arttext&pid=S0034-98872022001201619&lng=en&nrm=iso&tlng=en
dc.identifier.citationRevista Medica de Chile, Volume 150, Issue 12, Pages 1619 - 1624, December 2022
dc.identifier.doi10.4067/S0034-98872022001201619
dc.identifier.issn0034-9887
dc.identifier.urihttps://repositorio.unab.cl/handle/ria/55758
dc.language.isoes
dc.publisherSociedad Medica de Santiago
dc.rights.licenseCC BY 4.0 DEED Attribution 4.0 International
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/deed.en
dc.subjectAngioplasty
dc.subjectBalloon
dc.subjectCoronary
dc.subjectMyocardial Infarction
dc.subjectThrombolytic Therapy
dc.subjectCoronary Angiography
dc.subjectFibrinolytic Agents
dc.subjectHumans
dc.subjectMiddle Aged
dc.subjectST Elevation Myocardial Infarction
dc.subjectTreatment Outcome
dc.titlePharmaco-invasive approach in the management of acute myocardial infarction. Analysis of 144 cases
dc.title.alternativeEstrategia fármaco-invasiva en el manejo del infarto agudo al miocardio con supradesnivel del ST
dc.typeArtículo
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