Bookmarking the genome: Maintenance of epigenetic information

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dc.contributor.authorZaidi, S.
dc.contributor.authorYoung, D.
dc.contributor.authorMontecino, M.
dc.contributor.authorVan Wijnen, A.
dc.contributor.authorStein, J.
dc.contributor.authorLian, J.
dc.contributor.authorStein, G.
dc.date.accessioned2023-08-08T16:49:01Z
dc.date.available2023-08-08T16:49:01Z
dc.date.issued2011-05
dc.descriptionIndexación: Scopus.es
dc.description.abstractMitotic inheritance of gene function is obligatory to sustain biological control. Emerging evidence suggests that epigenetic mechanisms are linked to transmission of cell fate, lineage commitment, and maintenance of cellular phenotype in progeny cells. Mechanisms of epigenetic memory include gene silencing by DNA methylation, transcriptional regulation by histone modifications, regulation of gene expression by noncoding small RNA molecules, and retention of regulatory machinery on target gene loci for activation and repression. We will focus on the regulatory implications of epigenetic memory for physiological control and for the onset and progression of disease. © 2011 by The American Society for Biochemistry and Molecular Biology, Inc.es
dc.description.urihttps://www-sciencedirect-com.recursosbiblioteca.unab.cl/science/article/pii/S0021925820510922?via%3Dihub#ceack10
dc.identifier.citationJournal of Biological Chemistry, Volume 286, Issue 21, Pages 18355 - 18361, 27 May 2011es
dc.identifier.doi10.1074/jbc.R110.197061
dc.identifier.issn1083-351X
dc.identifier.urihttps://repositorio.unab.cl/xmlui/handle/ria/52309
dc.language.isoenes
dc.publisherElsevieres
dc.rights.licenseAttribution 4.0 International (CC BY 4.0)
dc.rights.urihttps://s100.copyright.com/AppDispatchServlet?publisherName=ELS&contentID=S0021925820510922&orderBeanReset=true
dc.subjectMitosises
dc.subjectChromatines
dc.subjectBookmarkinges
dc.titleBookmarking the genome: Maintenance of epigenetic informationes
dc.typeArtículoes
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