Metabolomic Analysis of Two Parmotrema Lichens: P. robustum (Degel.) Hale and P. andinum (Mull. Arg.) Hale Using UHPLC-ESI-OT-MS-MS

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dc.contributor.authorTorres-Benítez, A.
dc.contributor.authorRivera-Montalvo, M.
dc.contributor.authorSepúlveda, B.
dc.contributor.authorCastro, O.N.
dc.contributor.authorNagles, E.
dc.contributor.authorSimirgiotis, M.J.
dc.contributor.authorGarciá-Beltrán, O.
dc.contributor.authorAreche, C.
dc.date.accessioned2018-05-28T19:53:56Z
dc.date.available2018-05-28T19:53:56Z
dc.date.issued2017
dc.descriptionIndexación: Scopus.es_ES
dc.description.abstractLichens are symbiotic associations of fungi with microalgae and/or cyanobacteria. Lichens belonging to the Parmeliaceae family comprise 2700 species of lichens, including the Parmotrema genus which is composed of 300 species. The metabolites of this genus include depsides, depsidones, phenolics, polysaccharides, lipids, diphenylethers and dibenzofurans, which are responsible for the biological activities reported including antidiabetic, antihelmintic, anticancer, antioxidant, antibacterial, anti-inflammatory, antimitotic, antitumoral, antifungal, and antioxidant enzyme inhibitory. Due to scarce knowledge of metabolomic profiles of Parmotrema species (P. andinum and P. robustum), a full metabolome study based on ultra-high performance liquid chromatography-diode array detector-electrospray ionization-quadrupole-orbitrap-mass-spectrometry (UHPLC-DAD-ESI-Q-orbitrap MS) was performed for a comprehensive characterization of their substances. From the methanolic extracts of these species, a total of 54 metabolites were identified for the first time using this hyphenated technique, including thirty compounds in P. andinum, and thirty-seven in P. robustum. Moreover, two compounds were not identified as known compounds, and could be new structures, according to our data. This report shows that this technique is effective and accurate for rapid chemical identification of lichen substances and the compounds identified could serve as chemotaxonomic markers to differentiate these ruffle lichens.es_ES
dc.description.urihttp://www.mdpi.com/1420-3049/22/11/1861
dc.identifier.citationMolecules, 22(11), art. no. 1861.es_ES
dc.identifier.issn1420-3049
dc.identifier.otherDOI: 10.3390/molecules22111861
dc.identifier.urihttp://repositorio.unab.cl/xmlui/handle/ria/5903
dc.language.isoenes_ES
dc.publisherMDPI AGes_ES
dc.subjectElectrosprayes_ES
dc.subjectLichenses_ES
dc.subjectMetabolomices_ES
dc.subjectOrbitrapes_ES
dc.subjectParmotremaes_ES
dc.subjectUHPLC-MS-MSes_ES
dc.titleMetabolomic Analysis of Two Parmotrema Lichens: P. robustum (Degel.) Hale and P. andinum (Mull. Arg.) Hale Using UHPLC-ESI-OT-MS-MSes_ES
dc.typeArtículoes_ES
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