Examinando por Autor "Nova-Baeza, Pablo"

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    Anatomical characteristics, relations, and clinical considerations of the facial index and cephalic index in young chileans aged between 18 and 21 years
    (Universidad de la Frontera, 2023-12) Milos-Brandenberg, Daniel; Espinoza González, Dámaso; Valenzuela-Fuenzalida, Juan José; Nova-Baeza, Pablo; Orellana-Donoso, Mathias
    Humans throughout history have shown similarities between both their cephalic and facial complexion, among certain ethnic groups, due to genetic and demographic factors. Several studies have demonstrated the different constitutions of specific groups of people in order to generate data of a certain population or group. The present research aims to preliminarily study the existence of possible relations between Cephalic Index and Facial Index among categories of individuals in an odontology student population from a private university in Santiago, Chile. Empirical, descriptive, and cross-sectional study. In this study, 129 students with age range 18-21 were taken as subjects in a non-probabilistic way. Regarding Cephalic Index (CI), the Retzius classification was used, and the Facial Index (FI) was measured considering the maximum height of the face, from nasion to gnathion (Na-Gn), and the maximum width, from right zygion to left zygion (Zr-Zl). In this study, 129 people were taken as sample, 82 females and 47 males. Among women, the most predominant cephalic biotype was brachycephalic (59.8 %), followed by mesocephalic (37.8 %), and dolichocephalic (2.4 %). On the other hand, men’s most common biotype was mesocephalic (57.5 %), followed by brachycephalic (36.2 %), and dolichocephalic (6.4 %). Regarding facial biotype, both in female and male subjects the following pattern was shown: euryprosopic (F: 59.7 %, M: 59.6 %), mesoprosopic (F: 26.8 %, M: 29.8 %), and leptoprosopic (F: 13.4 %, M: 10.6 %). Facial parameters of the subjects (odontology students from a Chilean university) tend to be mostly euryprosopic, followed by mesoprosopic and leptoprosopic. Additionally, mesocephalic biotypes tend to be similar to other studies conducted in Chile. © 2023, Universidad de la Frontera. All rights reserved.
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    Clinical Characteristics of Neuropathic Pain and Its Relationship with Cancer in Different Corporal Areas—A Systematic Review
    (Multidisciplinary Digital Publishing Institute (MDPI), 0025-01) Danés-López, Fernanda; Diaz-Palominos, Cristóbal; Ortiz Domínguez, Anggie; Silva Rodriguez, Alanna; Astorga, Constanza; Martínez-Hernández, Daniela; Valenzuela-Fuenzalida, Juan Jose; Sanchis-Gimeno, Juan; Nova-Baeza, Pablo; Suazo-Santibáñez, Alejandra; Oyanedel-Amaro, Gustavo; Orellana-Donoso, Mathias
    Background: Neuropathic pain (NP) and cancer are caused by nerve damage due to cancer or treatments such as chemotherapy, radiotherapy, and surgery, with a prevalence that can reach up to 40%. Causes of neuropathic cancer pain (NCP) include direct nerve invasion or compression by the tumor, as well as neural toxicity associated with treatments. This type of pain is classified into several categories, such as plexopathy, radiculopathy, and peripheral neuropathies. Methods: Medline, Web of Science, Google Scholar, CINAHL, and LILACS databases were searched until October 2024. Two authors independently performed the search, study selection, and data extraction. Methodological quality was analyzed using the Robins-I tool. Results: The main findings of this review indicate that, depending on the cancer type, neuropathic pain will exhibit different characteristics, as well as identifying which types of cancer have a higher probability of presenting neuropathic pain. Additionally, there is a direct relationship whereby the more advanced the cancer, the greater the likelihood of experiencing neuropathic pain. Finally, although chemotherapy is employed as a cancer treatment, this therapy is quite invasive, and one of its adverse effects is that treated patients have a higher probability of developing neuropathic pain. Conclusions: Neuropathic pain is a condition that adversely affects patients with cancer. A detailed understanding of the relationships and triggers that produce this condition is present in only a small percentage of patients with cancer and is necessary to provide better treatment and gain a more comprehensive understanding of the characteristics of neuropathic pain. The objective of this study is to describe the relationship between different types of cancer or various treatments and the presence of NP. © 2025 by the authors.
  • No hay miniatura disponible
    Ítem
    Clinical Characteristics of Neuropathic Pain and Its Relationship with Cancer in Different Corporal Areas—A Systematic Review
    (Multidisciplinary Digital Publishing Institute (MDPI), 0025-01) Danés-López, Fernanda; Diaz-Palominos, Cristóbal; Ortiz Domínguez, Anggie; Silva Rodriguez, Alanna; Astorga, Constanza; Martínez-Hernández, Daniela; Valenzuela-Fuenzalida, Juan Jose; Sanchis-Gimeno, Juan; Nova-Baeza, Pablo; Suazo-Santibáñez, Alejandra; Oyanedel-Amaro, Gustavo; Orellana-Donoso, Mathias
    Background: Neuropathic pain (NP) and cancer are caused by nerve damage due to cancer or treatments such as chemotherapy, radiotherapy, and surgery, with a prevalence that can reach up to 40%. Causes of neuropathic cancer pain (NCP) include direct nerve invasion or compression by the tumor, as well as neural toxicity associated with treatments. This type of pain is classified into several categories, such as plexopathy, radiculopathy, and peripheral neuropathies. Methods: Medline, Web of Science, Google Scholar, CINAHL, and LILACS databases were searched until October 2024. Two authors independently performed the search, study selection, and data extraction. Methodological quality was analyzed using the Robins-I tool. Results: The main findings of this review indicate that, depending on the cancer type, neuropathic pain will exhibit different characteristics, as well as identifying which types of cancer have a higher probability of presenting neuropathic pain. Additionally, there is a direct relationship whereby the more advanced the cancer, the greater the likelihood of experiencing neuropathic pain. Finally, although chemotherapy is employed as a cancer treatment, this therapy is quite invasive, and one of its adverse effects is that treated patients have a higher probability of developing neuropathic pain. Conclusions: Neuropathic pain is a condition that adversely affects patients with cancer. A detailed understanding of the relationships and triggers that produce this condition is present in only a small percentage of patients with cancer and is necessary to provide better treatment and gain a more comprehensive understanding of the characteristics of neuropathic pain. The objective of this study is to describe the relationship between different types of cancer or various treatments and the presence of NP. © 2025 by the authors.
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    Effectiveness of alpha-lipoic acid in patients with neuropathic pain associated with type i and type II diabetes mellitus: A systematic review and meta-Analysis
    (Lippincott Williams and Wilkins, 2023-11) Orellana-Donoso, Mathias; López-Chaparro, Michelle; Barahona-Vásquez, Marisol; Santana-Machuca, Andrés; Bruna-Mejias, Alejandro; Nova-Baeza, Pablo; Valenzuela-Fuenzalida, Juan José
    Background: This systematic review explores the most current evidence regarding the mechanisms of neuropathic pain in patients with different types of diabetes and how this pain affects different functional and structural components of the neuroanatomical pain pathways. The review also seeks to provide guidelines for the best approach and treatment for patients experiencing this type of pain. The objective is to determine the effectiveness of alpha-lipoic acid (ALA) in improving functional and symptomatic outcomes in patients with diabetes mellitus type I and type II. Objective: To determine the effectiveness of alpha-lipoic acid (ALA) in improving functional and symptomatic outcomes in patients with diabetes mellitus type I and type II. Methods: We systematically search MEDLINE (via PubMed), EMBASE, SCOPUS, the Cochrane Central Register of Controlled Trials, the Cumulative Index to Nursing and Allied Health Literature, and Web of Science databases. Results: The findings of this review show that different forms of ALA do not present statistically significant changes for any of the scales included, including total symptom score (standardized mean difference [SMD] =-3.59, confidence interval [CI] =-4.16 to-3.02, and P <.00001), neuropathy impairment score (SMD =-1.42, CI =-3.68 to 0.84, and P =.22), and neuropathy symptom checklist (SMD =-0.09, CI =-0.15 to-0.02, and P =.01). Conclusion: In comparison to the use of a placebo, the findings suggest that ALA does not exhibit significant differences in terms of pain reduction and different functional scales. Moreover, no specific dosages are identified to support the use of ALA for the reduction of neuropathic pain. © 2023 Lippincott Williams and Wilkins. All rights reserved.
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    Hepatic Hilum Variations and Their Clinical Considerations in the Liver: A Systematic Review and Meta-Analysis
    (Multidisciplinary Digital Publishing Institute (MDPI), 0024-10) Valenzuela-Fuenzalida, Juan Jose; Pena-Santibañez, Fernanda; Vergara Salinas, Ayline; Meneses Caroca, Trinidad; Rojo-Gonzalez, Javiera; Orellana-Donoso, Mathias Ignacio; Nova-Baeza, Pablo; Suazo-Santibañez, Alejandra; Sanchis-Gimeno, Juan; Gutierrez-Espinoza, Hector
    Background: The liver has a region called the hepatic hilum (HH) where structures enter and exit: anteriorly, the left and right hepatic ducts; posteriorly, the portal vein; and between these, the left and right hepatic arteries. The objective of this review is to know how variants in structures of the hepatic hilum are associated with clinical alterations of the liver. Methods: The databases Medline, Scopus, Web of Science, Google Scholar, CINAHL, and LILACS were researched until January 2024. The methodological quality was evaluated with an assurance tool for anatomical studies (AQUA). The pooled prevalence was estimated using a random effects model. Results: A total of six studies met the selection criteria established in this study for meta-analysis. The prevalence of hepatic hilus variants was 9% (CI = 5% to 13%), and the heterogeneity was 83%. The other studies were analyzed descriptively and with their respective clinical considerations in the presence of the variant, such as the high incidence of the Michels type III variant; among the portal vein variants, the type III variant of the Cheng classification stands out and in biliary anatomy, and the IIIa variant stands out according to the Choi classification. Conclusions: This review allowed us to know in detail the anatomical variants of HH; the structure with which the greatest care should be taken is the hepatic artery because of the probability of metastatic processes due to increased blood distribution in the hepatic lobules. Finally, we believe that new anatomical and clinical studies are needed to improve our knowledge of the relationship between HH variants and liver alterations or surgeries. © 2024 by the authors.
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    Incidence and Clinical Implications of Anatomical Variations in the Pancreas and Its Ductal System: A Systematic Review and Meta-Analysis
    (Multidisciplinary Digital Publishing Institute (MDPI), 2023-08) Orellana-Donoso, Mathias; Milos-Brandenberg, Daniel; Benavente-Urtubia, Andoni; Guerra-Loyola, Javier; Bruna-Mejias, Alejandro; Nova-Baeza, Pablo; Becerra-Farfán, Álvaro; Sepulveda-Loyola, Walter; Luque-Bernal, Ricardo Miguel; Valenzuela-Fuenzalida, Juan José
    Objective: This systematic review analyzes the anatomical variants in the pancreas and its ductal system to report on their association with pancreatic pathologies. Methods: We conducted a search of the MEDLINE, Scopus, Web of Science, Google Scholar, CINAHL, and LILACS databases from their inception to July 2023. The methodological quality was assessed with the Anatomical Quality Assessment (AQUA) tool. Finally, the pooled prevalence was estimated using a random effects model. Results: 55 studies were found that met the eligibility criteria. The overall prevalence of pancreas divisum (PD) was 18% (95% CI = 15–21%). The prevalence of PD associated with pancreatitis was 30% (95% CI = 1–61%). Conclusions: An anatomical variant of the pancreas such as PD may be the cause of bile duct obstruction, resulting in various clinical complications, such as pancreatitis. Hence, knowing this variant is extremely important for surgeons, especially for those who treat the gastroduodenal region.
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    Prevalence of the Bifid Mandibular Condyle and Its Relationship with Pathologies of the Temporomandibular Joint: A Systematic Review and Meta-Analysis
    (MDPI, 2023-10) Valenzuela-Fuenzalida, Juan José; Navarro, Kora-lle Keller; Urbina, Pia; Trujillo-Riveros, Martin; Nova-Baeza, Pablo; Orellana-Donoso, Mathias; Rodriguez-Luengo, Macarena; Beccerra Farfan, Alvaro; Sanchis-Gimeno, Juan A.
    The aim of this study was to describe the prevalence of anatomical variants in the bifid mandibular condyle (BMC) and report its association with temporomandibular joint (TMJ) pathology. Methods: We searched the Medline, Scopus, Web of Science, Google Scholar, CINAHL, and LILACS databases from their inception up to September 2023. Two authors independently performed the search, study selection, and data extraction, and they also assessed the methodological quality with an assurance tool for anatomical studies (AQUA). Finally, the pooled prevalence was estimated using a random effects model. Results: A total of 50 studies met the eligibility criteria. Twenty studies, with a total of 88,625 subjects, were included in the meta-analysis. The overall prevalence of the bifid mandibular condyle (BMC) variant was 1% (95% CI = 1% to 2%). Conclusions: The correlation between the BMC and TMJ pathologies has a relatively low prevalence in studies that present a considerable number of subjects. From a clinical point of view, a direct association cannot be made between the presence of the BMC and TMJ pathologies or symptoms.