Examinando por Autor "Saez, J."

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    An IoT-Based Prototype for Optimizing Agricultural Irrigation: A Case Study in the Biobío Region of Chile
    (Procedia Computer Science, 2024) Saez, J.; Pantoja, J.; Matamala, M.; Briceño, I.; Vásconez, J.; Romero-Conrado, A.
    This paper shows an agricultural irrigation alternative using a low-cost Internet of Things (IoT) application. This technology allows the automation and optimization of processes by monitoring, processing, and analyzing large volumes of related data, including variables related to the soil (moisture), fertilization, and irrigation, which can be visualized through the internet to enable sustainable and efficient agriculture. The study is centered on the Los Angeles, Biobío, Chile case. The main objective of the prototype is to optimize water consumption for agricultural irrigation by using only the amount that is strictly necessary for each crop by allowing real-time visualization of irrigation status, moisture data, and irrigation times while providing a history of data that can be used for further analysis.
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    Transplant Tolerance: New Insights and Strategies for Long-Term Allograft Acceptance
    (Hindawi Limited, 2013) Ruiz, P.; Maldonado, P.; Hidalgo, Y.; Gleisner, A.; Sauma, D.; Silva, C.; Saez, J.; Nuñez, S.; Rosemblatt, M.; Bono, M.
    One of the greatest advances in medicine during the past century is the introduction of organ transplantation. This therapeutic strategy designed to treat organ failure and organ dysfunction allows to prolong the survival of many patients that are faced with no other treatment option. Today, organ transplantation between genetically dissimilar individuals (allogeneic grafting) is a procedure widely used as a therapeutic alternative in cases of organ failure, hematological disease treatment, and some malignancies. Despite the potential of organ transplantation, the administration of immunosuppressive drugs required for allograft acceptance induces severe immunosuppression in transplanted patients, which leads to serious side effects such as infection with opportunistic pathogens and the occurrence of neoplasias, in addition to the known intrinsic toxicity of these drugs. To solve this setback in allotransplantation, researchers have focused on manipulating the immune response in order to create a state of tolerance rather than unspecific immunosuppression. Here, we describe the different treatments and some of the novel immunotherapeutic strategies undertaken to induce transplantation tolerance.